Esterified estrogens/methyltestosterone

Esterified estrogens/methyltestosterone (EEs/MT), also known as estrified estrogens/methyltestosterone and sold under the brand name Menogen among others, is a combination of estrogen and androgen used to treat symptoms of menopause in women. It contains esterified estrogens and methyltestosterone.

Etymology

The term "esterified" refers to the process of forming an ester, a chemical compound derived from an acid. In this case, the estrogens are chemically modified to form esters. The term "methyltestosterone" refers to a synthetic form of the male sex hormone testosterone that has been modified by the addition of a methyl group.

Pharmacology

EEs/MT is a combination of esterified estrogens and methyltestosterone. Esterified estrogens are a mixture of several different estrogens that are derived from the urine of pregnant mares. Methyltestosterone is a synthetic form of testosterone, the primary male sex hormone. Together, these two hormones work to alleviate symptoms of menopause such as hot flashes and vaginal dryness.

Medical uses

EEs/MT is used primarily to treat symptoms of menopause in women. It can help to alleviate symptoms such as hot flashes, night sweats, mood swings, and vaginal dryness and atrophy. It may also be used to prevent osteoporosis in postmenopausal women.

Side effects

Like all medications, EEs/MT can cause side effects. Common side effects include nausea, vomiting, bloating, stomach cramps, changes in weight or appetite, and breast tenderness or swelling. More serious side effects can include mental/mood changes, severe stomach/abdominal pain, unusual tiredness, dark urine, and yellowing eyes/skin.

See also

• Estrogen
• Androgen
• Menopause
• Esterified estrogens
• Methyltestosterone

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