OR4C11

OR4C11 is a gene that encodes the olfactory receptor, family 4, subfamily C, member 11 in humans. The olfactory receptor proteins are members of a large family of G-protein coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome.

Function

The OR4C11 gene is a part of the olfactory receptor family, which is involved in the detection of smell. The olfactory receptors are located in the cell membranes of the olfactory receptor neurons and are responsible for the detection of odor molecules. The OR4C11 gene encodes a protein that is one of these receptors.

Structure

The OR4C11 gene is located on chromosome 11, and it spans approximately 1,000 base pairs. The gene encodes a protein that is 312 amino acids long. The protein is a 7-transmembrane G protein-coupled receptor, which is a common structure for olfactory receptors.

Clinical Significance

While the specific clinical significance of OR4C11 is not yet fully understood, olfactory receptors in general have been linked to various diseases and conditions. For example, mutations in olfactory receptor genes have been associated with anosmia, which is the inability to perceive smell. Further research is needed to determine the specific role of OR4C11 in human health and disease.

See Also

• Olfactory receptor
• G protein-coupled receptor
• Anosmia

References

<references />

   This article is a medical stub. You can help WikiMD by expanding it!