4,5-DHP-DMT

4,5-DHP-DMT (4,5-dihydroxy-N,N-dimethyltryptamine) is a psychedelic compound belonging to the tryptamine class. It is structurally related to other tryptamines such as DMT (N,N-dimethyltryptamine) and psilocin.

Chemical Structure and Properties

Chemical structure of 4,5-DHP-DMT

4,5-DHP-DMT is characterized by the presence of two hydroxyl groups at the 4 and 5 positions of the indole ring, which distinguishes it from other tryptamines. The chemical formula for 4,5-DHP-DMT is C12H16N2O2, and it has a molecular weight of 220.27 g/mol.

The presence of the hydroxyl groups makes 4,5-DHP-DMT more polar than its non-hydroxylated counterparts, potentially affecting its pharmacokinetics and interaction with biological systems.

Pharmacology

4,5-DHP-DMT is believed to act as a serotonin receptor agonist, similar to other psychedelic tryptamines. It likely interacts with the 5-HT2A receptor, which is thought to be responsible for the psychedelic effects of these compounds. However, detailed studies on its receptor binding profile and pharmacodynamics are limited.

Effects

The effects of 4,5-DHP-DMT are not well-documented in scientific literature. However, based on its structural similarity to other tryptamines, it may produce altered states of consciousness, visual and auditory hallucinations, and changes in perception and mood. The intensity and duration of these effects can vary depending on the dose and individual differences.

Synthesis

The synthesis of 4,5-DHP-DMT involves the hydroxylation of DMT at the 4 and 5 positions. This can be achieved through various chemical reactions, but specific synthetic routes are not widely published in the literature.

Legal Status

The legal status of 4,5-DHP-DMT varies by country. In many jurisdictions, it may be considered a controlled substance due to its structural similarity to other regulated tryptamines. Researchers and individuals interested in this compound should consult local regulations before handling or studying it.

Related Compounds

• DMT
• Psilocin
• Bufotenin
• 5-MeO-DMT

Related Pages

• Tryptamine
• Psychedelic drug
• Serotonin receptor