Tafenoquine

Tafenoquine is an antimalarial medication used for the prevention and treatment of malaria. It is specifically used to prevent relapse of Plasmodium vivax and Plasmodium ovale malaria. Tafenoquine is taken by mouth and is available as a generic medication.

Medical uses

Tafenoquine is used for the prevention and treatment of malaria caused by Plasmodium vivax and Plasmodium ovale. It is also used to prevent malaria in individuals traveling to areas where malaria is common. Tafenoquine is not recommended for use in individuals with a history of psychosis or other psychiatric disorders.

Side effects

Common side effects of tafenoquine include nausea, vomiting, and dizziness. Serious side effects may include anemia, methemoglobinemia, and psychiatric effects such as anxiety and depression. Tafenoquine is not recommended for use during pregnancy or breastfeeding due to potential harm to the baby.

Pharmacology

Tafenoquine works by interfering with the growth of parasites in the red blood cells of the human body. Parasites that cause malaria typically enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia.

History

Tafenoquine was approved for medical use in the United States in 2018. It is on the World Health Organization's List of Essential Medicines, the safest and most effective medicines needed in a health system.

References

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