Carbocromen
Carbocromen is a vasodilator and antianginal medication. It is used in the treatment of angina pectoris, a condition characterized by chest pain due to reduced blood flow to the heart. Carbocromen works by relaxing and widening blood vessels, thereby improving blood flow to the heart muscle.
Mechanism of Action
Carbocromen acts as a phosphodiesterase inhibitor, which means it blocks the action of an enzyme called phosphodiesterase. This enzyme is responsible for breaking down cyclic adenosine monophosphate (cAMP), a molecule that plays a crucial role in many biological processes, including the relaxation of smooth muscle tissue. By inhibiting phosphodiesterase, Carbocromen increases the levels of cAMP, leading to relaxation and dilation of blood vessels.
Indications
Carbocromen is indicated for the treatment of angina pectoris. It may also be used in the management of other cardiovascular conditions where improved blood flow is beneficial, such as coronary artery disease and peripheral artery disease.
Side Effects
Like all medications, Carbocromen can cause side effects. Common side effects include headache, dizziness, and flushing. Less common side effects may include nausea, vomiting, and palpitations. Severe side effects are rare but can include hypotension (low blood pressure), tachycardia (fast heart rate), and arrhythmia (irregular heart rhythm).
Contraindications
Carbocromen is contraindicated in patients with known hypersensitivity to the drug. It should also be used with caution in patients with severe liver or kidney disease, as these conditions may affect the metabolism and excretion of the drug.
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