Dogiel cells

Dogiel cells are a type of neuron found in the autonomic nervous system. They were first described by the Russian histologist, Alexei Ivanovich Dogiel, after whom they are named.

Etymology

The term "Dogiel cells" is derived from the name of the Russian histologist, Alexei Ivanovich Dogiel, who first described these cells.

Description

Dogiel cells are characterized by their distinct morphology and are classified into two types: Type I and Type II.

Type I Dogiel cells are found in the myenteric plexus and have a single axon that branches out into the muscle layers of the gut. These cells are involved in the regulation of gastrointestinal motility.

Type II Dogiel cells are located in the submucosal plexus and have multiple short dendrites. These cells are involved in the regulation of secretion and blood flow in the gut.

Function

Dogiel cells play a crucial role in the functioning of the autonomic nervous system. They are involved in the regulation of various physiological processes such as gastrointestinal motility, secretion, and blood flow in the gut.

Clinical significance

Abnormalities in Dogiel cells have been associated with various gastrointestinal disorders such as Irritable Bowel Syndrome (IBS) and Inflammatory Bowel Disease (IBD).

See also

• Neuron
• Autonomic nervous system
• Myenteric plexus
• Submucosal plexus

References

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