Ornidazole

Ornidazole is a drug that is used in the treatment of protozoan infections. It has a similar mechanism of action as metronidazole.

Pharmacology

Ornidazole is a 5-nitroimidazole derivative that is used in the treatment of infections caused by protozoa and anaerobic bacteria. It works by inhibiting the structure of the microorganism's DNA, leading to the death of the bacteria or protozoa.

Medical uses

Ornidazole is used in the treatment of a variety of protozoan infections, including giardiasis, trichomoniasis, and amoebiasis. It is also used in the treatment of infections caused by anaerobic bacteria, such as bacterial vaginosis.

Side effects

Common side effects of ornidazole include nausea, vomiting, headache, dizziness, and a metallic taste in the mouth. In rare cases, it can cause seizures or peripheral neuropathy.

Contraindications

Ornidazole should not be used in individuals with a known hypersensitivity to 5-nitroimidazole derivatives. It should also be used with caution in individuals with a history of seizure disorders or neurological conditions.

Interactions

Ornidazole can interact with alcohol, leading to a disulfiram-like reaction. It can also interact with warfarin, leading to an increased risk of bleeding.

Pharmacokinetics

Ornidazole is well absorbed after oral administration and is widely distributed in the body. It is metabolized in the liver and excreted in the urine and feces.

See also

• Metronidazole
• Tinidazole

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