Zyklophin

Zyklophin is a synthetic peptide that acts as a selective kappa opioid receptor antagonist. It was developed by researchers at the National Institutes of Health (NIH) and has been used in scientific research to study the role of kappa opioid receptors in the brain and body.

History

Zyklophin was first synthesized in the early 21st century as part of a research program at the NIH aimed at developing new tools for studying the opioid system. The compound was designed to be a selective antagonist for the kappa opioid receptor, one of the three main types of opioid receptors in the body.

Pharmacology

Zyklophin is a selective antagonist for the kappa opioid receptor. This means that it binds to this receptor and blocks its activation by other substances. This property has made Zyklophin a valuable tool for researchers studying the role of the kappa opioid receptor in various physiological and pathological processes.

Uses in Research

Zyklophin has been used in a variety of research contexts. For example, it has been used to study the role of the kappa opioid receptor in pain perception, mood regulation, and the body's response to stress. It has also been used to investigate the potential therapeutic benefits of kappa opioid receptor antagonists in the treatment of conditions such as depression, anxiety, and addiction.

Safety and Side Effects

As a research tool, Zyklophin is not intended for human consumption. Therefore, its safety profile and potential side effects have not been thoroughly studied. However, as a kappa opioid receptor antagonist, it is expected to have a similar side effect profile to other drugs in this class.

See Also

• Kappa opioid receptor
• Opioid receptor
• Peptide

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