Delayed hemolytic transfusion reaction
| Delayed hemolytic transfusion reaction | |
|---|---|
| Synonyms | DHTR |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Fever, jaundice, anemia, hemoglobinuria |
| Complications | Renal failure, disseminated intravascular coagulation |
| Onset | Typically 3 to 10 days after transfusion |
| Duration | Variable, depending on severity |
| Types | N/A |
| Causes | Alloimmunization to red blood cell antigens |
| Risks | Previous transfusions, pregnancy, sickle cell disease |
| Diagnosis | Direct antiglobulin test, antibody screen, hemoglobin level |
| Differential diagnosis | Acute hemolytic transfusion reaction, autoimmune hemolytic anemia |
| Prevention | Careful blood typing and crossmatching |
| Treatment | Supportive care, corticosteroids, intravenous immunoglobulin |
| Medication | N/A |
| Prognosis | N/A |
| Frequency | Rare |
| Deaths | N/A |
A delayed hemolytic transfusion reaction (DHTR) is a type of transfusion reaction. According to the Centers for disease Control's (CDC) National Healthcare Safety Network's (NHSN) Hemovigilance Module, it is defined as:
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