VU-0152100

VU-0152100

Chemical structure of VU-0152100

VU-0152100 is a chemical compound that acts as a selective antagonist for the M5 muscarinic receptor. It is used primarily in scientific research to study the role of the M5 receptor in various physiological processes.

Chemical Properties

VU-0152100 has the IUPAC name 3-((3-chlorophenyl)carbamoyl)-1-benzylpyridin-1-ium chloride. It is a small molecule with a molecular formula of C19H16Cl2N2O and a molecular weight of 359.25 g/mol. The compound is typically synthesized in a laboratory setting and is not found naturally.

Mechanism of Action

As an antagonist of the M5 muscarinic receptor, VU-0152100 binds to this receptor and inhibits its activity. The M5 receptor is one of the five subtypes of muscarinic receptors, which are part of the G protein-coupled receptor family. These receptors are activated by the neurotransmitter acetylcholine. The M5 receptor is less well understood than the other muscarinic receptors, but it is believed to play a role in modulating dopamine release in the brain.

Research Applications

VU-0152100 is used in research to explore the function of the M5 receptor. Studies have suggested that the M5 receptor may be involved in the regulation of reward pathways and addiction. By using VU-0152100 to block the M5 receptor, researchers can investigate how this receptor influences these processes. Additionally, VU-0152100 has been used in studies examining the potential therapeutic applications of M5 receptor modulation in conditions such as schizophrenia and Parkinson's disease.

Related Pages

• Muscarinic acetylcholine receptor
• G protein-coupled receptor
• Dopamine
• Neurotransmitter