Progastricsin
Progastricsin (also known as pepsinogen C) is a zymogen secreted by the gastric chief cells in the stomach. It is an aspartic protease that is activated to its active form, pepsin, in the acidic environment of the stomach.
Function
Progastricsin is involved in the digestion of proteins in the stomach. It is secreted as an inactive precursor, which is then converted into the active enzyme pepsin by the acidic pH of the stomach. This conversion involves the cleavage of a peptide bond in the progastricsin molecule, resulting in the active enzyme.
Clinical significance
Elevated levels of progastricsin in the blood can be indicative of certain gastric diseases, such as gastritis or gastric cancer. It is often measured in conjunction with other biomarkers to assess gastric function and health.
See also
References
External links
Ad. Transform your life with W8MD's
GLP-1 weight loss injections special from $29.99 with insurance
|
WikiMD Medical Encyclopedia |
Medical Disclaimer: WikiMD is for informational purposes only and is not a substitute for professional medical advice. Content may be inaccurate or outdated and should not be used for diagnosis or treatment. Always consult your healthcare provider for medical decisions. Verify information with trusted sources such as CDC.gov and NIH.gov. By using this site, you agree that WikiMD is not liable for any outcomes related to its content. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
