OR2D2

OR2D2

Symbol	OR2D2
HGNC ID	8181
Alternative symbols	–
Entrez Gene	–
OMIM	–
RefSeq	–
UniProt	–
Chromosome	6q23
Locus supplementary data	–

OR2D2 is a gene that encodes a member of the olfactory receptor family of proteins. These proteins are involved in the detection of odor molecules and are part of the G protein-coupled receptor (GPCR) superfamily.

Function

Olfactory receptors, such as OR2D2, are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor proteins share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors, which allows them to interact with odorant molecules in the olfactory epithelium and initiate a neuronal response that triggers the perception of a smell.

Gene Family

The olfactory receptor gene family is the largest in the human genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. OR2D2 is part of the olfactory receptor family 2, subfamily D, member 2.

Location

The OR2D2 gene is located on the long arm (q) of chromosome 6 at position 23. This location is significant for the study of genetic linkage and association with various traits and conditions.

Clinical Significance

While the primary function of OR2D2 is related to olfaction, variations in olfactory receptor genes have been studied for potential links to olfactory disorders and other conditions. However, specific clinical implications of OR2D2 variations are not well-documented and require further research.

Research

Research into olfactory receptors like OR2D2 continues to expand our understanding of sensory perception and its genetic basis. Studies often focus on the diversity of olfactory receptors and their evolutionary significance.

See Also

• Olfactory receptor
• G protein-coupled receptor
• Chromosome 6

External Links

• OR2D2 Gene - NCBI
• OR2D2 Gene - GeneCards