Prurigo nodularis: Difference between revisions
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{{Infobox medical condition | |||
| name = Prurigo nodularis | |||
| image = [[File:Prurigo_nodularis.jpg|alt=Prurigo nodularis]] | |||
| caption = Prurigo nodularis lesions on the skin | |||
| synonyms = Nodular prurigo | |||
| specialty = [[Dermatology]] | |||
| symptoms = [[Itchiness]], [[nodules]] on the skin | |||
| complications = [[Infection]], [[scarring]] | |||
| onset = Any age, more common in adults | |||
| duration = Chronic | |||
| causes = Unknown, possibly related to [[atopic dermatitis]], [[insect bites]], or other skin conditions | |||
| risks = [[Atopy]], [[HIV/AIDS]], [[chronic kidney disease]] | |||
| diagnosis = [[Clinical diagnosis]], [[skin biopsy]] | |||
| differential = [[Lichen simplex chronicus]], [[dermatitis herpetiformis]], [[cutaneous lymphoma]] | |||
| treatment = [[Topical corticosteroids]], [[antihistamines]], [[phototherapy]], [[immunomodulators]] | |||
| prognosis = Variable, often chronic and relapsing | |||
| frequency = Rare | |||
}} | |||
[[File:Nodularis_prurigo.jpg|Nodularis prurigo|thumb|left]] | |||
'''Prurigo nodularis''' ('''PN''') is a chronic [[dermatology|dermatological]] condition characterized by itchy nodules which usually appear on the arms or legs. Patients often present with multiple excoriated nodules caused by scratching. The condition is also known as '''Hyde's prurigo'''. | '''Prurigo nodularis''' ('''PN''') is a chronic [[dermatology|dermatological]] condition characterized by itchy nodules which usually appear on the arms or legs. Patients often present with multiple excoriated nodules caused by scratching. The condition is also known as '''Hyde's prurigo'''. | ||
==Etiology== | ==Etiology== | ||
The exact cause of prurigo nodularis is unknown, but it is often associated with other underlying conditions such as [[kidney disease]], [[HIV]], and [[hepatitis]]. It is also more common in people with a history of [[atopic dermatitis]], [[asthma]], or [[hay fever]]. | The exact cause of prurigo nodularis is unknown, but it is often associated with other underlying conditions such as [[kidney disease]], [[HIV]], and [[hepatitis]]. It is also more common in people with a history of [[atopic dermatitis]], [[asthma]], or [[hay fever]]. | ||
==Symptoms== | ==Symptoms== | ||
The primary symptom of prurigo nodularis is intensely itchy nodules on the skin. These nodules can range in size from a few millimeters to several centimeters in diameter. They are usually found on the arms and legs, but can appear anywhere on the body. The itching can be severe enough to interfere with sleep and daily activities. | The primary symptom of prurigo nodularis is intensely itchy nodules on the skin. These nodules can range in size from a few millimeters to several centimeters in diameter. They are usually found on the arms and legs, but can appear anywhere on the body. The itching can be severe enough to interfere with sleep and daily activities. | ||
==Diagnosis== | ==Diagnosis== | ||
Diagnosis of prurigo nodularis is primarily based on the clinical presentation of the characteristic nodules. A [[biopsy]] may be performed to confirm the diagnosis and rule out other conditions. | Diagnosis of prurigo nodularis is primarily based on the clinical presentation of the characteristic nodules. A [[biopsy]] may be performed to confirm the diagnosis and rule out other conditions. | ||
==Treatment== | ==Treatment== | ||
Treatment of prurigo nodularis can be challenging and often requires a multi-faceted approach. Topical treatments such as [[corticosteroid]] creams and [[capsaicin]] cream can help to reduce itching. In severe cases, systemic treatments such as [[immunosuppressant]] drugs may be used. Phototherapy is another treatment option. | Treatment of prurigo nodularis can be challenging and often requires a multi-faceted approach. Topical treatments such as [[corticosteroid]] creams and [[capsaicin]] cream can help to reduce itching. In severe cases, systemic treatments such as [[immunosuppressant]] drugs may be used. Phototherapy is another treatment option. | ||
==Prognosis== | ==Prognosis== | ||
The prognosis for prurigo nodularis varies. Some people find relief with treatment, while others may experience persistent symptoms. The condition does not affect life expectancy, but can significantly impact quality of life due to the intense itching and discomfort. | The prognosis for prurigo nodularis varies. Some people find relief with treatment, while others may experience persistent symptoms. The condition does not affect life expectancy, but can significantly impact quality of life due to the intense itching and discomfort. | ||
[[Category:Dermatology]] | [[Category:Dermatology]] | ||
[[Category:Skin conditions]] | [[Category:Skin conditions]] | ||
[[Category:Chronic diseases]] | [[Category:Chronic diseases]] | ||
{{medicine-stub}} | {{medicine-stub}} | ||
Latest revision as of 05:37, 9 April 2025
Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC
| Prurigo nodularis | |
|---|---|
| |
| Synonyms | Nodular prurigo |
| Pronounce | N/A |
| Specialty | Dermatology |
| Symptoms | Itchiness, nodules on the skin |
| Complications | Infection, scarring |
| Onset | Any age, more common in adults |
| Duration | Chronic |
| Types | N/A |
| Causes | Unknown, possibly related to atopic dermatitis, insect bites, or other skin conditions |
| Risks | Atopy, HIV/AIDS, chronic kidney disease |
| Diagnosis | Clinical diagnosis, skin biopsy |
| Differential diagnosis | Lichen simplex chronicus, dermatitis herpetiformis, cutaneous lymphoma |
| Prevention | N/A |
| Treatment | Topical corticosteroids, antihistamines, phototherapy, immunomodulators |
| Medication | N/A |
| Prognosis | Variable, often chronic and relapsing |
| Frequency | Rare |
| Deaths | N/A |
Prurigo nodularis (PN) is a chronic dermatological condition characterized by itchy nodules which usually appear on the arms or legs. Patients often present with multiple excoriated nodules caused by scratching. The condition is also known as Hyde's prurigo.
Etiology[edit]
The exact cause of prurigo nodularis is unknown, but it is often associated with other underlying conditions such as kidney disease, HIV, and hepatitis. It is also more common in people with a history of atopic dermatitis, asthma, or hay fever.
Symptoms[edit]
The primary symptom of prurigo nodularis is intensely itchy nodules on the skin. These nodules can range in size from a few millimeters to several centimeters in diameter. They are usually found on the arms and legs, but can appear anywhere on the body. The itching can be severe enough to interfere with sleep and daily activities.
Diagnosis[edit]
Diagnosis of prurigo nodularis is primarily based on the clinical presentation of the characteristic nodules. A biopsy may be performed to confirm the diagnosis and rule out other conditions.
Treatment[edit]
Treatment of prurigo nodularis can be challenging and often requires a multi-faceted approach. Topical treatments such as corticosteroid creams and capsaicin cream can help to reduce itching. In severe cases, systemic treatments such as immunosuppressant drugs may be used. Phototherapy is another treatment option.
Prognosis[edit]
The prognosis for prurigo nodularis varies. Some people find relief with treatment, while others may experience persistent symptoms. The condition does not affect life expectancy, but can significantly impact quality of life due to the intense itching and discomfort.
