Hibernoma: Difference between revisions

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{{SI}}
{{Infobox medical condition
| name            = Hibernoma
| image          = [[File:Hibernoma1.jpg]]
| caption        = Histopathological image of a hibernoma
| field          = [[Oncology]]
| synonyms        =
| symptoms        = Usually asymptomatic, may present as a painless mass
| complications  = Rarely, compression of adjacent structures
| onset          = Typically in adults
| duration        = Indefinite
| causes          = Unknown
| risks          =
| diagnosis      = [[Histopathology]], [[Imaging studies]]
| differential    = [[Liposarcoma]], [[Lipoma]], [[Myxoid liposarcoma]]
| prevention      = None
| treatment      = [[Surgical excision]]
| medication      = None
| prognosis      = Excellent with complete excision
| frequency      = Rare
}}
[[File:Hibernoma2.jpg|Hibernoma|left|thumb]]
'''Hibernoma''' is a rare, benign [[tumor]] that originates from brown [[fat tissue]]. The name "hibernoma" is derived from the tumor's resemblance to the brown fat found in hibernating animals.  
'''Hibernoma''' is a rare, benign [[tumor]] that originates from brown [[fat tissue]]. The name "hibernoma" is derived from the tumor's resemblance to the brown fat found in hibernating animals.  
== History ==
== History ==
The first known case of hibernoma was reported by Merkel in 1906. Since then, fewer than 200 cases have been reported in the medical literature.
The first known case of hibernoma was reported by Merkel in 1906. Since then, fewer than 200 cases have been reported in the medical literature.
== Pathology ==
== Pathology ==
Hibernomas are composed of brown fat cells, which are larger than white fat cells and contain more [[mitochondria]]. These cells are responsible for heat production in the body, a process known as [[thermogenesis]].  
Hibernomas are composed of brown fat cells, which are larger than white fat cells and contain more [[mitochondria]]. These cells are responsible for heat production in the body, a process known as [[thermogenesis]].  
== Clinical Presentation ==
== Clinical Presentation ==
Patients with hibernoma often present with a slow-growing, painless mass. The most common locations for hibernomas are the thigh, shoulder, back, and neck.  
Patients with hibernoma often present with a slow-growing, painless mass. The most common locations for hibernomas are the thigh, shoulder, back, and neck.  
== Diagnosis ==
== Diagnosis ==
The diagnosis of hibernoma is typically made through a combination of [[imaging studies]] and [[biopsy]]. On imaging, hibernomas appear as well-defined, vascular masses. The definitive diagnosis is made by biopsy, which shows the characteristic brown fat cells.
The diagnosis of hibernoma is typically made through a combination of [[imaging studies]] and [[biopsy]]. On imaging, hibernomas appear as well-defined, vascular masses. The definitive diagnosis is made by biopsy, which shows the characteristic brown fat cells.
== Treatment ==
== Treatment ==
The treatment for hibernoma is surgical removal. Because hibernomas are benign, they do not spread to other parts of the body, and complete removal is usually curative.
The treatment for hibernoma is surgical removal. Because hibernomas are benign, they do not spread to other parts of the body, and complete removal is usually curative.
== Prognosis ==
== Prognosis ==
The prognosis for patients with hibernoma is excellent. After surgical removal, the recurrence rate is very low.
The prognosis for patients with hibernoma is excellent. After surgical removal, the recurrence rate is very low.
== See Also ==
== See Also ==
* [[Lipoma]]
* [[Lipoma]]
* [[Liposarcoma]]
* [[Liposarcoma]]
* [[Benign tumors]]
* [[Benign tumors]]
[[Category:Medical conditions]]
[[Category:Medical conditions]]
[[Category:Tumors]]
[[Category:Tumors]]
[[Category:Rare diseases]]
[[Category:Rare diseases]]
{{stub}}
{{stub}}
<gallery>
File:Neck_Hibernoma_Eosinophilic_Cell_type_H&E_LDRT.tif|Neck Hibernoma Eosinophilic Cell type H&E
File:Hibernoma2.jpg|Hibernoma
</gallery>

Latest revision as of 04:13, 9 April 2025

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC

Hibernoma
Synonyms
Pronounce N/A
Specialty N/A
Symptoms Usually asymptomatic, may present as a painless mass
Complications Rarely, compression of adjacent structures
Onset Typically in adults
Duration Indefinite
Types N/A
Causes Unknown
Risks
Diagnosis Histopathology, Imaging studies
Differential diagnosis Liposarcoma, Lipoma, Myxoid liposarcoma
Prevention None
Treatment Surgical excision
Medication None
Prognosis Excellent with complete excision
Frequency Rare
Deaths N/A


Hibernoma

Hibernoma is a rare, benign tumor that originates from brown fat tissue. The name "hibernoma" is derived from the tumor's resemblance to the brown fat found in hibernating animals.

History[edit]

The first known case of hibernoma was reported by Merkel in 1906. Since then, fewer than 200 cases have been reported in the medical literature.

Pathology[edit]

Hibernomas are composed of brown fat cells, which are larger than white fat cells and contain more mitochondria. These cells are responsible for heat production in the body, a process known as thermogenesis.

Clinical Presentation[edit]

Patients with hibernoma often present with a slow-growing, painless mass. The most common locations for hibernomas are the thigh, shoulder, back, and neck.

Diagnosis[edit]

The diagnosis of hibernoma is typically made through a combination of imaging studies and biopsy. On imaging, hibernomas appear as well-defined, vascular masses. The definitive diagnosis is made by biopsy, which shows the characteristic brown fat cells.

Treatment[edit]

The treatment for hibernoma is surgical removal. Because hibernomas are benign, they do not spread to other parts of the body, and complete removal is usually curative.

Prognosis[edit]

The prognosis for patients with hibernoma is excellent. After surgical removal, the recurrence rate is very low.

See Also[edit]

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