Iron-deficiency anemia: Difference between revisions

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{{SI}}
{{Infobox medical condition
| name            = Iron-deficiency anemia
| image          = [[File:redbloodcells.jpg|250px]]
| caption        = Micrograph showing [[hypochromic]] [[microcytic anemia]], characteristic of iron-deficiency anemia
| field          = [[Hematology]]
| symptoms        = [[Fatigue (medical)|Fatigue]], [[pallor]], [[shortness of breath]], [[dizziness]], [[headache]], [[cold hands and feet]], [[brittle nails]]
| complications  = [[Heart failure]], [[pregnancy complications]], [[growth problems in children]]
| onset          = Gradual
| duration        = Varies
| causes          = [[Iron deficiency]] due to [[dietary deficiency]], [[blood loss]], [[malabsorption]], [[increased demand]]
| risks          = [[Menstruation]], [[pregnancy]], [[infants]], [[vegetarian diet]]
| diagnosis      = [[Complete blood count]], [[serum ferritin]], [[serum iron]], [[total iron-binding capacity]]
| differential    = [[Thalassemia]], [[anemia of chronic disease]], [[sideroblastic anemia]]
| prevention      = [[Iron-rich diet]], [[iron supplements]]
| treatment      = [[Iron supplements]], [[dietary changes]], [[treating underlying cause]]
| medication      = [[Oral iron supplements]], [[intravenous iron]]
| frequency      = Common
| deaths          = Rare
}}
'''Iron-deficiency anemia''' is a prevalent type of [[anemia]] that occurs when there is an insufficient amount of iron in the body. Individuals with mild to moderate iron-deficiency anemia may not exhibit any signs or symptoms, while more severe cases can lead to fatigue, shortness of breath, or chest pain.
'''Iron-deficiency anemia''' is a prevalent type of [[anemia]] that occurs when there is an insufficient amount of iron in the body. Individuals with mild to moderate iron-deficiency anemia may not exhibit any signs or symptoms, while more severe cases can lead to fatigue, shortness of breath, or chest pain.
== Causes ==
== Causes ==
[[File:Iron deficiency anemia blood film.jpg|thumb|Human blood from a case of iron deficiency anemia (Giemsa stain)]]
[[File:Iron deficiency anemia blood film.jpg|left|thumb|Human blood from a case of iron deficiency anemia (Giemsa stain)]]
Iron-deficiency anemia typically develops gradually due to various factors:
Iron-deficiency anemia typically develops gradually due to various factors:
=== <u>Blood Loss</u> ===
=== <u>Blood Loss</u> ===
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=== <u>Sex</u> ===
=== <u>Sex</u> ===
* Girls and women between the ages of 14 and 50, particularly during menstruation, pregnancy, or breastfeeding.
* Girls and women between the ages of 14 and 50, particularly during menstruation, pregnancy, or breastfeeding.
== Screening and Prevention ==
== Screening and Prevention ==
Screening for iron-deficiency anemia may be recommended based on risk factors, including pregnancy. Prevention strategies may include dietary changes and managing conditions contributing to iron deficiency.
Screening for iron-deficiency anemia may be recommended based on risk factors, including pregnancy. Prevention strategies may include dietary changes and managing conditions contributing to iron deficiency.
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=== <u>Prevention Strategies</u> ===
=== <u>Prevention Strategies</u> ===
Consuming iron-rich foods and increasing vitamin C intake can aid iron absorption. Delayed clamping of the newborn's umbilical cord may prevent anemia in infants.
Consuming iron-rich foods and increasing vitamin C intake can aid iron absorption. Delayed clamping of the newborn's umbilical cord may prevent anemia in infants.
== Signs, Symptoms, and Complications ==
== Signs, Symptoms, and Complications ==
Iron-deficiency anemia can vary in severity, with symptoms worsening as the condition progresses. Complications may arise if left untreated.
Iron-deficiency anemia can vary in severity, with symptoms worsening as the condition progresses. Complications may arise if left untreated.
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=== <u>Complications</u> ===
=== <u>Complications</u> ===
Untreated anemia can lead to heart problems, increased infection risk, and developmental delays in children.
Untreated anemia can lead to heart problems, increased infection risk, and developmental delays in children.
== Diagnosis ==
== Diagnosis ==
Diagnosing iron-deficiency anemia involves physical exams, blood tests, and potentially, tests for gastrointestinal bleeding.
Diagnosing iron-deficiency anemia involves physical exams, blood tests, and potentially, tests for gastrointestinal bleeding.
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=== <u>Blood Tests</u> ===
=== <u>Blood Tests</u> ===
Tests like CBC, iron levels, and ferritin levels help diagnose anemia and determine its severity.
Tests like CBC, iron levels, and ferritin levels help diagnose anemia and determine its severity.
== Treatment ==
== Treatment ==
Treatment options depend on the cause and severity of the anemia and may include iron supplements, intravenous iron therapy, or blood transfusions.
Treatment options depend on the cause and severity of the anemia and may include iron supplements, intravenous iron therapy, or blood transfusions.
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=== <u>Other Treatments</u> ===
=== <u>Other Treatments</u> ===
Erythropoiesis stimulating agents (ESA) may be recommended for individuals with chronic kidney disease.
Erythropoiesis stimulating agents (ESA) may be recommended for individuals with chronic kidney disease.
== Living With ==
== Living With ==
Following the treatment plan, monitoring symptoms, and preventing complications are essential aspects of managing iron-deficiency anemia.
Following the treatment plan, monitoring symptoms, and preventing complications are essential aspects of managing iron-deficiency anemia.
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=== <u>Learn Precautions</u> ===
=== <u>Learn Precautions</u> ===
Understanding precautions for activities and medication interactions is important for safety.
Understanding precautions for activities and medication interactions is important for safety.
== See also ==
== See also ==
* [[Anemia]]
* [[Anemia]]
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* [[Iron]]
* [[Iron]]
* [[Red blood cells]]
* [[Red blood cells]]
[[Category:Anemia]]
[[Category:Anemia]]
[[Category:Iron]]
[[Category:Iron]]
[[Category:Blood disorders]]
[[Category:Blood disorders]]
[[Category:Medical conditions]]
[[Category:Medical conditions]]
{{stub}}
{{stub}}

Latest revision as of 00:35, 8 April 2025

Editor-In-Chief: Prab R Tumpati, MD
Obesity, Sleep & Internal medicine
Founder, WikiMD Wellnesspedia &
W8MD medical weight loss NYC and sleep center NYC

Iron-deficiency anemia
Synonyms N/A
Pronounce N/A
Specialty N/A
Symptoms Fatigue, pallor, shortness of breath, dizziness, headache, cold hands and feet, brittle nails
Complications Heart failure, pregnancy complications, growth problems in children
Onset Gradual
Duration Varies
Types N/A
Causes Iron deficiency due to dietary deficiency, blood loss, malabsorption, increased demand
Risks Menstruation, pregnancy, infants, vegetarian diet
Diagnosis Complete blood count, serum ferritin, serum iron, total iron-binding capacity
Differential diagnosis Thalassemia, anemia of chronic disease, sideroblastic anemia
Prevention Iron-rich diet, iron supplements
Treatment Iron supplements, dietary changes, treating underlying cause
Medication Oral iron supplements, intravenous iron
Prognosis N/A
Frequency Common
Deaths Rare


Iron-deficiency anemia is a prevalent type of anemia that occurs when there is an insufficient amount of iron in the body. Individuals with mild to moderate iron-deficiency anemia may not exhibit any signs or symptoms, while more severe cases can lead to fatigue, shortness of breath, or chest pain.

Causes[edit]

Human blood from a case of iron deficiency anemia (Giemsa stain)

Iron-deficiency anemia typically develops gradually due to various factors:

Blood Loss[edit]

  • Bleeding in the gastrointestinal tract, which can result from ulcers, colon cancer, or the regular use of medications like aspirin or nonsteroidal anti-inflammatory drugs (NSAIDs).
  • Certain genetic conditions such as hereditary hemorrhagic telangiectasia.
  • Frequent blood donation or blood tests.
  • Heavy menstrual periods.
  • Injury, surgery, or urinary tract bleeding.

Consuming Less Iron[edit]

  • Inadequate intake of iron-rich foods.

Problems Absorbing Iron[edit]

  • Digestive conditions like celiac disease or inflammatory bowel diseases.
  • Previous gastrointestinal surgeries.
  • Rare genetic conditions affecting iron absorption.

Other Medical Conditions[edit]

  • End-stage kidney failure or chronic kidney disease.
  • Inflammation from congestive heart failure or obesity.

Risk Factors[edit]

Several factors can increase the risk of developing iron-deficiency anemia:

Age[edit]

  • Infants between 6 and 12 months.
  • Children between ages 1 and 2.
  • Teens undergoing growth spurts.
  • Older adults, especially those over age 65.

Unhealthy Environments[edit]

  • Children exposed to lead.

Family History and Genetics[edit]

  • Inherited bleeding disorders like Von Willebrand disease or hemophilia.

Lifestyle Habits[edit]

  • Vegetarian or vegan eating patterns.
  • Frequent blood donation.
  • Participation in endurance activities.

Sex[edit]

  • Girls and women between the ages of 14 and 50, particularly during menstruation, pregnancy, or breastfeeding.

Screening and Prevention[edit]

Screening for iron-deficiency anemia may be recommended based on risk factors, including pregnancy. Prevention strategies may include dietary changes and managing conditions contributing to iron deficiency.

Blood Tests[edit]

Routine blood tests like complete blood count (CBC) can detect anemia, while further tests may be necessary to identify the underlying cause.

Prevention Strategies[edit]

Consuming iron-rich foods and increasing vitamin C intake can aid iron absorption. Delayed clamping of the newborn's umbilical cord may prevent anemia in infants.

Signs, Symptoms, and Complications[edit]

Iron-deficiency anemia can vary in severity, with symptoms worsening as the condition progresses. Complications may arise if left untreated.

Signs and Symptoms[edit]

Common signs include brittle nails, pale skin, and spooning of the nails, while symptoms range from fatigue to irregular heartbeat.

Complications[edit]

Untreated anemia can lead to heart problems, increased infection risk, and developmental delays in children.

Diagnosis[edit]

Diagnosing iron-deficiency anemia involves physical exams, blood tests, and potentially, tests for gastrointestinal bleeding.

Physical Exam[edit]

Doctors may check for signs like pale skin, brittle nails, or irregular heartbeats.

Blood Tests[edit]

Tests like CBC, iron levels, and ferritin levels help diagnose anemia and determine its severity.

Treatment[edit]

Treatment options depend on the cause and severity of the anemia and may include iron supplements, intravenous iron therapy, or blood transfusions.

Iron Supplements[edit]

Oral iron supplements are commonly prescribed to replenish iron levels.

Procedures[edit]

In severe cases, intravenous iron therapy or blood transfusions may be necessary.

Healthy Lifestyle Changes[edit]

Adopting a balanced diet rich in iron and vitamin C can aid in treatment.

Other Treatments[edit]

Erythropoiesis stimulating agents (ESA) may be recommended for individuals with chronic kidney disease.

Living With[edit]

Following the treatment plan, monitoring symptoms, and preventing complications are essential aspects of managing iron-deficiency anemia.

Follow Your Treatment Plan[edit]

Adhering to prescribed treatments and reporting any side effects to your doctor is crucial.

Monitor Your Condition[edit]

Regular check-ups and monitoring of symptoms can help track progress.

Prevent Complications[edit]

Maintaining a healthy lifestyle and managing underlying conditions can prevent complications.

Learn Warning Signs[edit]

Being aware of symptoms worsening can prompt timely medical attention.

Learn Precautions[edit]

Understanding precautions for activities and medication interactions is important for safety.

See also[edit]

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