Basaloid follicular hamartoma: Difference between revisions
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{{SI}} | |||
{{Infobox medical condition | |||
| name = Basaloid follicular hamartoma | |||
| image = [[File:SkinTumors-P6040183.JPG|left|thumb|Basaloid follicular hamartoma]] | |||
| caption = Basaloid follicular hamartoma | |||
| synonyms = | |||
| pronounce = | |||
| specialty = [[Dermatology]] | |||
| symptoms = Skin-colored papules, plaques | |||
| complications = | |||
| onset = | |||
| duration = | |||
| types = | |||
| causes = Genetic mutations | |||
| risks = | |||
| diagnosis = [[Skin biopsy]] | |||
| differential = [[Basal cell carcinoma]], [[Trichoepithelioma]] | |||
| prevention = | |||
| treatment = [[Surgical excision]], [[Laser therapy]] | |||
| medication = | |||
| prognosis = Generally benign | |||
| frequency = Rare | |||
}} | |||
'''Basaloid follicular hamartoma''' is a rare, benign [[skin lesion]] that is characterized by its histological resemblance to [[basal cell carcinoma]] and other [[skin diseases]]. It was first described in the medical literature in 1985. | '''Basaloid follicular hamartoma''' is a rare, benign [[skin lesion]] that is characterized by its histological resemblance to [[basal cell carcinoma]] and other [[skin diseases]]. It was first described in the medical literature in 1985. | ||
==Clinical Presentation== | ==Clinical Presentation== | ||
[[Basaloid follicular hamartoma]]s typically present as solitary or multiple skin-colored papules or nodules. They can be found anywhere on the body, but are most commonly located on the face, scalp, and neck. The lesions are usually asymptomatic, but can sometimes cause mild itching or discomfort. | [[Basaloid follicular hamartoma]]s typically present as solitary or multiple skin-colored papules or nodules. They can be found anywhere on the body, but are most commonly located on the face, scalp, and neck. The lesions are usually asymptomatic, but can sometimes cause mild itching or discomfort. | ||
==Pathogenesis== | ==Pathogenesis== | ||
The exact cause of [[basaloid follicular hamartoma]]s is unknown. However, they are thought to result from an abnormal proliferation of the basaloid cells in the hair follicles. Some cases have been associated with genetic disorders such as [[Gorlin syndrome]] and [[Cowden syndrome]], suggesting a possible genetic component to their development. | The exact cause of [[basaloid follicular hamartoma]]s is unknown. However, they are thought to result from an abnormal proliferation of the basaloid cells in the hair follicles. Some cases have been associated with genetic disorders such as [[Gorlin syndrome]] and [[Cowden syndrome]], suggesting a possible genetic component to their development. | ||
==Diagnosis== | ==Diagnosis== | ||
Diagnosis of a [[basaloid follicular hamartoma]] is typically made based on the clinical presentation and histological examination of a skin biopsy. The histology shows a proliferation of basaloid cells forming follicular structures, with a characteristic "jigsaw puzzle" pattern. The lesions are typically well-circumscribed and lack the aggressive features seen in basal cell carcinoma. | Diagnosis of a [[basaloid follicular hamartoma]] is typically made based on the clinical presentation and histological examination of a skin biopsy. The histology shows a proliferation of basaloid cells forming follicular structures, with a characteristic "jigsaw puzzle" pattern. The lesions are typically well-circumscribed and lack the aggressive features seen in basal cell carcinoma. | ||
==Treatment== | ==Treatment== | ||
Treatment for [[basaloid follicular hamartoma]]s is usually not necessary, as they are benign and do not cause significant symptoms. However, if the lesions are bothersome or cosmetically unacceptable, they can be removed with surgical excision or laser therapy. | Treatment for [[basaloid follicular hamartoma]]s is usually not necessary, as they are benign and do not cause significant symptoms. However, if the lesions are bothersome or cosmetically unacceptable, they can be removed with surgical excision or laser therapy. | ||
==Prognosis== | ==Prognosis== | ||
The prognosis for individuals with [[basaloid follicular hamartoma]]s is generally good. The lesions are benign and do not have the potential to become malignant. However, they can sometimes be associated with other systemic diseases, so individuals with these lesions should be monitored for the development of other symptoms. | The prognosis for individuals with [[basaloid follicular hamartoma]]s is generally good. The lesions are benign and do not have the potential to become malignant. However, they can sometimes be associated with other systemic diseases, so individuals with these lesions should be monitored for the development of other symptoms. | ||
[[Category:Dermatology]] | [[Category:Dermatology]] | ||
[[Category:Skin conditions]] | [[Category:Skin conditions]] | ||
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{{Dermatology-stub}} | {{Dermatology-stub}} | ||
{{Rare diseases-stub}} | {{Rare diseases-stub}} | ||
Latest revision as of 18:19, 4 April 2025
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| Basaloid follicular hamartoma | |
|---|---|
 | |
| Synonyms | |
| Pronounce | |
| Specialty | Dermatology |
| Symptoms | Skin-colored papules, plaques |
| Complications | |
| Onset | |
| Duration | |
| Types | |
| Causes | Genetic mutations |
| Risks | |
| Diagnosis | Skin biopsy |
| Differential diagnosis | Basal cell carcinoma, Trichoepithelioma |
| Prevention | |
| Treatment | Surgical excision, Laser therapy |
| Medication | |
| Prognosis | Generally benign |
| Frequency | Rare |
| Deaths | N/A |
Basaloid follicular hamartoma is a rare, benign skin lesion that is characterized by its histological resemblance to basal cell carcinoma and other skin diseases. It was first described in the medical literature in 1985.
Clinical Presentation[edit]
Basaloid follicular hamartomas typically present as solitary or multiple skin-colored papules or nodules. They can be found anywhere on the body, but are most commonly located on the face, scalp, and neck. The lesions are usually asymptomatic, but can sometimes cause mild itching or discomfort.
Pathogenesis[edit]
The exact cause of basaloid follicular hamartomas is unknown. However, they are thought to result from an abnormal proliferation of the basaloid cells in the hair follicles. Some cases have been associated with genetic disorders such as Gorlin syndrome and Cowden syndrome, suggesting a possible genetic component to their development.
Diagnosis[edit]
Diagnosis of a basaloid follicular hamartoma is typically made based on the clinical presentation and histological examination of a skin biopsy. The histology shows a proliferation of basaloid cells forming follicular structures, with a characteristic "jigsaw puzzle" pattern. The lesions are typically well-circumscribed and lack the aggressive features seen in basal cell carcinoma.
Treatment[edit]
Treatment for basaloid follicular hamartomas is usually not necessary, as they are benign and do not cause significant symptoms. However, if the lesions are bothersome or cosmetically unacceptable, they can be removed with surgical excision or laser therapy.
Prognosis[edit]
The prognosis for individuals with basaloid follicular hamartomas is generally good. The lesions are benign and do not have the potential to become malignant. However, they can sometimes be associated with other systemic diseases, so individuals with these lesions should be monitored for the development of other symptoms.
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