Pancreaticobiliary maljunction: Difference between revisions
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{{Infobox medical condition | |||
| name = Pancreaticobiliary maljunction | |||
| synonyms = PBM | |||
| field = [[Gastroenterology]] | |||
| symptoms = [[Abdominal pain]], [[jaundice]], [[pancreatitis]], [[cholangitis]] | |||
| complications = [[Biliary cancer]], [[pancreatic cancer]] | |||
| onset = Usually in [[childhood]] or [[adulthood]] | |||
| duration = Chronic | |||
| causes = Congenital anomaly | |||
| risks = [[Biliary tract cancer]], [[pancreatic cancer]] | |||
| diagnosis = [[Magnetic resonance cholangiopancreatography]] (MRCP), [[Endoscopic retrograde cholangiopancreatography]] (ERCP) | |||
| differential = [[Choledochal cyst]], [[biliary atresia]] | |||
| treatment = [[Surgical intervention]], [[endoscopic therapy]] | |||
| medication = [[Analgesics]], [[antibiotics]] for infections | |||
| frequency = Rare | |||
| deaths = Related to complications such as cancer | |||
}} | |||
'''Pancreaticobiliary maljunction''' (PBM) is a rare congenital anomaly characterized by a union of the pancreatic and biliary ducts located outside the duodenal wall. This condition is associated with an increased risk of [[biliary tract cancer]] and [[gallbladder cancer]]. | '''Pancreaticobiliary maljunction''' (PBM) is a rare congenital anomaly characterized by a union of the pancreatic and biliary ducts located outside the duodenal wall. This condition is associated with an increased risk of [[biliary tract cancer]] and [[gallbladder cancer]]. | ||
== Anatomy == | == Anatomy == | ||
The [[pancreas]] and [[biliary tract]] are two separate systems in the body that aid in digestion. The pancreas produces enzymes that help break down food, while the biliary tract produces bile that helps the body absorb fats. In individuals with PBM, these two systems are connected, which can lead to various health complications. | The [[pancreas]] and [[biliary tract]] are two separate systems in the body that aid in digestion. The pancreas produces enzymes that help break down food, while the biliary tract produces bile that helps the body absorb fats. In individuals with PBM, these two systems are connected, which can lead to various health complications. | ||
== Pathophysiology == | == Pathophysiology == | ||
In PBM, the junction of the pancreatic and biliary ducts is located outside the duodenal wall, usually within the head of the pancreas. This abnormal junction allows pancreatic juice to reflux into the biliary tract, leading to inflammation, increased pressure, and potential for malignancy. | In PBM, the junction of the pancreatic and biliary ducts is located outside the duodenal wall, usually within the head of the pancreas. This abnormal junction allows pancreatic juice to reflux into the biliary tract, leading to inflammation, increased pressure, and potential for malignancy. | ||
== Symptoms == | == Symptoms == | ||
Symptoms of PBM can vary greatly depending on the individual and the severity of the condition. Some individuals may experience no symptoms, while others may experience abdominal pain, jaundice, or recurrent pancreatitis. | Symptoms of PBM can vary greatly depending on the individual and the severity of the condition. Some individuals may experience no symptoms, while others may experience abdominal pain, jaundice, or recurrent pancreatitis. | ||
== Diagnosis == | == Diagnosis == | ||
Diagnosis of PBM is typically made through imaging studies such as [[magnetic resonance cholangiopancreatography]] (MRCP), [[endoscopic retrograde cholangiopancreatography]] (ERCP), or [[ultrasound]]. These imaging studies can help visualize the pancreatic and biliary ducts and identify any abnormalities. | Diagnosis of PBM is typically made through imaging studies such as [[magnetic resonance cholangiopancreatography]] (MRCP), [[endoscopic retrograde cholangiopancreatography]] (ERCP), or [[ultrasound]]. These imaging studies can help visualize the pancreatic and biliary ducts and identify any abnormalities. | ||
== Treatment == | == Treatment == | ||
Treatment for PBM typically involves surgery to correct the abnormal junction of the pancreatic and biliary ducts. This can help prevent complications such as biliary tract cancer and gallbladder cancer. | Treatment for PBM typically involves surgery to correct the abnormal junction of the pancreatic and biliary ducts. This can help prevent complications such as biliary tract cancer and gallbladder cancer. | ||
== See also == | == See also == | ||
* [[Pancreas]] | * [[Pancreas]] | ||
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* [[Gallbladder cancer]] | * [[Gallbladder cancer]] | ||
* [[Biliary tract cancer]] | * [[Biliary tract cancer]] | ||
[[Category:Digestive system]] | [[Category:Digestive system]] | ||
[[Category:Congenital disorders]] | [[Category:Congenital disorders]] | ||
[[Category:Rare diseases]] | [[Category:Rare diseases]] | ||
{{stub}} | {{stub}} | ||
{{No image}} | {{No image}} | ||
Latest revision as of 04:34, 4 April 2025
| Pancreaticobiliary maljunction | |
|---|---|
| Synonyms | PBM |
| Pronounce | N/A |
| Specialty | N/A |
| Symptoms | Abdominal pain, jaundice, pancreatitis, cholangitis |
| Complications | Biliary cancer, pancreatic cancer |
| Onset | Usually in childhood or adulthood |
| Duration | Chronic |
| Types | N/A |
| Causes | Congenital anomaly |
| Risks | Biliary tract cancer, pancreatic cancer |
| Diagnosis | Magnetic resonance cholangiopancreatography (MRCP), Endoscopic retrograde cholangiopancreatography (ERCP) |
| Differential diagnosis | Choledochal cyst, biliary atresia |
| Prevention | N/A |
| Treatment | Surgical intervention, endoscopic therapy |
| Medication | Analgesics, antibiotics for infections |
| Prognosis | N/A |
| Frequency | Rare |
| Deaths | Related to complications such as cancer |
Pancreaticobiliary maljunction (PBM) is a rare congenital anomaly characterized by a union of the pancreatic and biliary ducts located outside the duodenal wall. This condition is associated with an increased risk of biliary tract cancer and gallbladder cancer.
Anatomy[edit]
The pancreas and biliary tract are two separate systems in the body that aid in digestion. The pancreas produces enzymes that help break down food, while the biliary tract produces bile that helps the body absorb fats. In individuals with PBM, these two systems are connected, which can lead to various health complications.
Pathophysiology[edit]
In PBM, the junction of the pancreatic and biliary ducts is located outside the duodenal wall, usually within the head of the pancreas. This abnormal junction allows pancreatic juice to reflux into the biliary tract, leading to inflammation, increased pressure, and potential for malignancy.
Symptoms[edit]
Symptoms of PBM can vary greatly depending on the individual and the severity of the condition. Some individuals may experience no symptoms, while others may experience abdominal pain, jaundice, or recurrent pancreatitis.
Diagnosis[edit]
Diagnosis of PBM is typically made through imaging studies such as magnetic resonance cholangiopancreatography (MRCP), endoscopic retrograde cholangiopancreatography (ERCP), or ultrasound. These imaging studies can help visualize the pancreatic and biliary ducts and identify any abnormalities.
Treatment[edit]
Treatment for PBM typically involves surgery to correct the abnormal junction of the pancreatic and biliary ducts. This can help prevent complications such as biliary tract cancer and gallbladder cancer.
