Corticosteroid-induced lipodystrophy

Corticosteroid-induced lipodystrophy
Synonyms	Steroid-induced lipodystrophy
Pronounce	N/A
Specialty	N/A
Symptoms	Fat redistribution, moon face, buffalo hump, central obesity, thin limbs
Complications	Insulin resistance, type 2 diabetes, dyslipidemia, hypertension
Onset	After initiation of corticosteroid therapy
Duration	Variable, often persists with continued corticosteroid use
Types	N/A
Causes	Use of corticosteroids
Risks	High-dose or long-term corticosteroid therapy
Diagnosis	Clinical evaluation, history of corticosteroid use
Differential diagnosis	Cushing's syndrome, lipodystrophy
Prevention	Use of lowest effective dose of corticosteroids, lifestyle modification
Treatment	Dose reduction of corticosteroids, dietary changes, exercise
Medication	N/A
Prognosis	Variable, may improve with reduction or cessation of corticosteroids
Frequency	Common in patients on long-term corticosteroid therapy
Deaths	N/A

Corticosteroid-induced lipodystrophy is a medical condition characterized by abnormal fat distribution in the body, caused by long-term use of corticosteroid drugs. This condition is a type of lipodystrophy, which refers to any abnormality in the metabolism or distribution of fats in the body.

Causes

Corticosteroid-induced lipodystrophy is primarily caused by the prolonged use of corticosteroid drugs. Corticosteroids are a class of steroid hormones that are often used to reduce inflammation and suppress the immune system. They are commonly used to treat conditions such as asthma, rheumatoid arthritis, and lupus.

Symptoms

The symptoms of corticosteroid-induced lipodystrophy can vary, but often include:

• Redistribution of body fat, particularly to the face (causing a "moon face"), back of the neck ("buffalo hump"), and abdomen
• Thinning of the arms and legs
• Increased appetite and weight gain
• Skin changes, such as thinning skin and easy bruising

Diagnosis

The diagnosis of corticosteroid-induced lipodystrophy is typically based on the patient's medical history and physical examination. The doctor may also order blood tests to rule out other conditions that can cause similar symptoms, such as Cushing's syndrome.

Treatment

The primary treatment for corticosteroid-induced lipodystrophy is to reduce or discontinue the use of corticosteroids, if possible. However, this must be done under the supervision of a healthcare provider, as abruptly stopping corticosteroids can lead to serious side effects. Other treatments may include lifestyle changes, such as diet and exercise, and medication to manage symptoms.

See also

• Corticosteroids
• Lipodystrophy
• Cushing's syndrome

References

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