Mayer waves: Difference between revisions

From WikiMD's Wellness Encyclopedia

m 1 revision imported
 
CSV import
 
Line 1: Line 1:
<!-- Important: please do not remove the above line. -->
{{Short description|Oscillations in arterial blood pressure}}
'''Mayer waves''' are cyclic changes or ''waves'' in [[artery|arterial]] [[blood pressure]] brought about by oscillations in [[baroreceptor]] and [[chemoreceptor]] reflex control systems.<ref name="Julien">{{cite journal|doi=10.1016/j.cardiores.2005.11.008|title=The enigma of Mayer waves: Facts and models.|year=2006|author=Julien C.|journal=Cardiovasc. Res.|volume=70 |pages=12–21|issue=1 |pmid=16360130}}</ref><ref>{{cite journal|doi=10.1111/j.1440-1681.1991.tb01391.x|title=Effects of respiration on blood pressure and heart rate variability in humans|year=1991|vauthors=Elghozi JL, Laude D, Girard A |journal=Clin Exp Pharmacol Physiol|volume=18 |pages=735–42|issue=11 |pmid=1782721}}</ref> The waves are seen both in the [[ECG]] and in continuous [[blood pressure]] curves and have a frequency about 0.1&nbsp;Hz (10-second waves). These waves were originally described by [[Siegmund Mayer]], Ewald Hering and [[Ludwig Traube (physician)|Ludwig Traube]] hence originally called "Traube–Hering–Mayer waves".


Mayer waves can be defined as arterial blood pressure (AP) oscillations at frequencies ''slower'' than respiratory frequency and  which show the strongest, significant coherence (strength of linear coupling between fluctuations of two variables in the frequency domain) with efferent sympathetic nervous activity (SNA). In humans, AP oscillations which meet these properties have a characteristic frequency of approx. 0.1&nbsp;Hz; 0.3&nbsp;Hz in rabbits and 0.4&nbsp;Hz in rats.<ref name="Julien"/>
'''Mayer waves''' are rhythmic oscillations in arterial blood pressure that occur at a frequency of approximately 0.1 Hz in humans. These waves are named after the German physiologist Siegmund Mayer, who first described them in 1876. Mayer waves are an important physiological phenomenon and are thought to be related to the autonomic regulation of blood pressure.


The hemodynamic basis of Mayer waves are oscillations of the sympathetic vasomotor tone of arterial blood vessels, because Mayer waves are abolished or at least strongly attenuated by pharmacological blockade of alpha-adrenoreceptors.<ref name="Julien"/> Within a given biological species, their frequency is fairly stable; in humans it has been shown that this frequency does ''not'' depend on gender, age or posture.<ref name="Julien"/> It has been suggested that Mayer waves trigger the liberation of endothelium-derived nitric oxide (NO) by cyclic changes of vascular shear stress which could be beneficial to end organ functioning.<ref name="Julien"/>
==Physiology==
Mayer waves are believed to be generated by the [[baroreflex]], a feedback mechanism that helps maintain stable blood pressure. The baroreflex involves sensors known as [[baroreceptors]], which are located in the [[carotid sinus]] and [[aortic arch]]. These receptors detect changes in blood pressure and send signals to the [[central nervous system]], which in turn adjusts the [[heart rate]] and [[vascular resistance]] to stabilize blood pressure.


Mayer waves are correlated with [[heart rate variability]].<ref>{{Cite journal|last=Bergfeldt|first=Lennart|last2=Haga|first2=Yoshiyuki|date=2003-06-01|title=Power spectral and Poincaré plot characteristics in sinus node dysfunction|journal=Journal of Applied Physiology|language=en|volume=94|issue=6|pages=2217–2224|doi=10.1152/japplphysiol.01037.2002|issn=8750-7587|pmid=12576413}}</ref>
The oscillations of Mayer waves are thought to arise from the interaction between the baroreflex and the [[autonomic nervous system]], particularly the [[sympathetic nervous system]]. When blood pressure rises, the baroreflex activates, leading to a decrease in sympathetic activity and a reduction in heart rate and vascular resistance. Conversely, when blood pressure falls, sympathetic activity increases, raising heart rate and vascular resistance. This feedback loop creates the characteristic oscillations of Mayer waves.


Takalo et al. (1999) state that "the frequency shift of Mayer waves to lower frequencies is associated with an increased risk of developing established [[hypertension]]."<ref>{{Cite news
==Clinical Significance==
| last = Takalo | last2 = Korhonen | last3 = Majahalme | last4 = Tuomisto | last5 = Turjanmaa
Mayer waves are of interest in both clinical and research settings. They can be used as a non-invasive measure of autonomic function and baroreflex sensitivity. Abnormalities in Mayer wave patterns may indicate dysfunction in autonomic regulation, which can be associated with various cardiovascular and neurological disorders.
| first = Reijo | first2 = Ilkka | first3 = Silja | first4 = Martti | first5 = Väinö
| publication-date = 1 February 1999 | date = 20 April 1998 | year = 1999
| title = Circadian profile of low-frequency oscillations in blood pressure and heart rate in hypertension
| periodical = [[American Journal of Hypertension]] | publisher = [[Nature Publishing Group]] | volume = 12 | pages = 874&ndash;881
| url = http://www.nature.com/ajh/journal/v12/n9/abs/ajh1999140a.html
| pmid = 10509544 | doi = 10.1016/S0895-7061(99)00069-2| issn = 0895-7061 | oclc = 645292880 | accessdate = 6 March 2011
| issue = 9
| postscript = <!-- Bot inserted parameter. Either remove it; or change its value to "." for the cite to end in a ".", as necessary. -->{{inconsistent citations}}
}}</ref>


== See also ==
In clinical practice, Mayer waves can be observed using [[continuous blood pressure monitoring]] techniques, such as [[finger photoplethysmography]] or [[arterial catheterization]]. These methods allow for the detection of the low-frequency oscillations characteristic of Mayer waves.
* [[Vasomotion]]


== References ==
==Research Applications==
{{reflist}}
Mayer waves are studied in various research contexts to understand the mechanisms of blood pressure regulation and the role of the autonomic nervous system. They are also used to investigate the effects of different interventions, such as [[pharmacological agents]], on autonomic function and cardiovascular health.


[[Category:Medical terminology]]
Research on Mayer waves has expanded our understanding of the complex interactions between the cardiovascular and nervous systems. It has also provided insights into the pathophysiology of conditions such as [[hypertension]], [[heart failure]], and [[autonomic neuropathy]].
 
==Related Pages==
* [[Baroreflex]]
* [[Autonomic nervous system]]
* [[Blood pressure]]
* [[Sympathetic nervous system]]
* [[Heart rate variability]]
 
[[Category:Cardiovascular physiology]]
[[Category:Autonomic nervous system]]

Latest revision as of 19:20, 22 March 2025

Oscillations in arterial blood pressure


Mayer waves are rhythmic oscillations in arterial blood pressure that occur at a frequency of approximately 0.1 Hz in humans. These waves are named after the German physiologist Siegmund Mayer, who first described them in 1876. Mayer waves are an important physiological phenomenon and are thought to be related to the autonomic regulation of blood pressure.

Physiology[edit]

Mayer waves are believed to be generated by the baroreflex, a feedback mechanism that helps maintain stable blood pressure. The baroreflex involves sensors known as baroreceptors, which are located in the carotid sinus and aortic arch. These receptors detect changes in blood pressure and send signals to the central nervous system, which in turn adjusts the heart rate and vascular resistance to stabilize blood pressure.

The oscillations of Mayer waves are thought to arise from the interaction between the baroreflex and the autonomic nervous system, particularly the sympathetic nervous system. When blood pressure rises, the baroreflex activates, leading to a decrease in sympathetic activity and a reduction in heart rate and vascular resistance. Conversely, when blood pressure falls, sympathetic activity increases, raising heart rate and vascular resistance. This feedback loop creates the characteristic oscillations of Mayer waves.

Clinical Significance[edit]

Mayer waves are of interest in both clinical and research settings. They can be used as a non-invasive measure of autonomic function and baroreflex sensitivity. Abnormalities in Mayer wave patterns may indicate dysfunction in autonomic regulation, which can be associated with various cardiovascular and neurological disorders.

In clinical practice, Mayer waves can be observed using continuous blood pressure monitoring techniques, such as finger photoplethysmography or arterial catheterization. These methods allow for the detection of the low-frequency oscillations characteristic of Mayer waves.

Research Applications[edit]

Mayer waves are studied in various research contexts to understand the mechanisms of blood pressure regulation and the role of the autonomic nervous system. They are also used to investigate the effects of different interventions, such as pharmacological agents, on autonomic function and cardiovascular health.

Research on Mayer waves has expanded our understanding of the complex interactions between the cardiovascular and nervous systems. It has also provided insights into the pathophysiology of conditions such as hypertension, heart failure, and autonomic neuropathy.

Related Pages[edit]