W-18

W-18 is a synthetic opioid and an analgesic drug which was first developed in the 1980s by chemists at the University of Alberta. It is one of 32 compounds in a series starting with W-1. W-18 is the most potent compound in the series, being approximately 10,000 times more potent than morphine.

History

W-18 was first synthesized in the 1980s by a team of chemists at the University of Alberta who were working on novel methods for synthesizing opioids. The compound was patented in 1984, but it was not until the 2010s that it began to appear in the illicit drug market.

Pharmacology

W-18 is a opioid and an analgesic drug. It is one of 32 compounds in a series starting with W-1, with W-18 being the most potent. It is approximately 10,000 times more potent than morphine, making it one of the most potent opioids known.

The exact mechanism of action of W-18 is not well understood. It is thought to act as a G protein-coupled receptor agonist, similar to other opioids. However, it has also been suggested that it may have additional mechanisms of action, which could contribute to its extreme potency.

Legal status

W-18 is a controlled substance in many countries, including the United States, Canada, and the United Kingdom. In the United States, it is classified as a Schedule I drug under the Controlled Substances Act, meaning it has a high potential for abuse and no accepted medical use.

Health risks

Due to its extreme potency, W-18 poses significant health risks. Overdose can occur at very low doses and can result in respiratory depression, coma, and death. There is also a high risk of addiction and dependence.

See also

• Fentanyl
• Carfentanil
• Opioid epidemic

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