GCT

Giant Cell Tumor (GCT) is a rare, typically benign (non-cancerous) tumor that usually develops near a joint at the end of the bone. The most common locations for GCT are in the knee and wrist. GCTs are sometimes aggressive and if not completely removed, they can lead to a local recurrence of the tumor.

Symptoms

The most common symptoms of GCT are pain and swelling in the affected area. Other symptoms may include limited range of motion in the affected joint, weakness, and fatigue.

Causes

The exact cause of GCT is unknown. It is not associated with any known risk factors or genetic mutations.

Diagnosis

Diagnosis of GCT typically involves a physical examination, imaging tests such as X-rays, CT scans, or MRI, and a biopsy of the tumor.

Treatment

Treatment options for GCT include surgery to remove the tumor, radiation therapy, and targeted therapy with drugs that block the growth of the tumor cells.

Prognosis

The prognosis for GCT is generally good, especially if the tumor is detected early and completely removed. However, GCTs can sometimes be aggressive and if not completely removed, they can lead to a local recurrence of the tumor.

See Also

• Bone Tumor
• Benign Tumor
• Cancer
• Radiation Therapy
• Surgery

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