TAS2R8

TAS2R8 is a gene that provides instructions for making a protein that is part of a family of taste receptors known as bitter taste receptors. These receptors are located on the surface of certain cells in the taste buds, which are clusters of cells that make up the sensory organs for taste.

Function

The TAS2R8 protein is a member of the TAS2R taste receptor family. It is thought to function in the perception of the bitterness of substances. The TAS2R proteins are G protein-coupled receptors that stimulate a signaling pathway to perceive the taste of bitter. This pathway begins with the binding of a specific bitter substance to the TAS2R8 receptor.

Clinical significance

Variations in the TAS2R8 gene have been associated with differences in taste perception, particularly the perception of bitter taste. Some studies suggest that these variations may influence dietary habits and potentially health outcomes.

See also

• Taste receptor
• TAS2R
• G protein-coupled receptor

References

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