OR51Q1

OR51Q1 is a protein that in humans is encoded by the OR51Q1 gene. The protein is a member of the olfactory receptor family, which is involved in the detection of smell.

Function

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome.

Gene

The OR51Q1 gene is located on chromosome 11 (11q11). It spans 1,065 base pairs and encodes a protein of 315 amino acids. The gene is expressed in the olfactory epithelium, where it is believed to play a role in odor detection.

Clinical significance

While the exact role of OR51Q1 in human health and disease is not fully understood, olfactory receptors such as OR51Q1 are believed to have roles in various physiological and pathological processes. These include sperm chemotaxis, the immune response, and cancer development and progression. Further research is needed to elucidate the specific roles of OR51Q1 in these processes.

See also

• Olfactory receptor
• G protein-coupled receptor
• Chromosome 11 (human)

References

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