OR13G1

OR13G1 is a gene that in humans is encoded by the OR13G1 protein. It is a member of the olfactory receptor family of genes, which are the largest gene family in the genome. The olfactory receptors (ORs) are G protein-coupled receptors that play a role in the detection of odorants.

Function

Olfactory receptors function by interacting with odorant molecules in the nose, initiating a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein coupled receptors (GPCR) arising from single coding-exon genes.

Gene

The OR13G1 gene is located on chromosome 1, specifically on the long (q) arm of chromosome 1 at position 36.11. The exact location is from base pair 24,000,000 to base pair 24,100,000.

Protein

The OR13G1 protein is a member of the G protein-coupled receptors (GPCRs) family. GPCRs are a large protein family of receptors that sense molecules outside the cell and activate inside signal transduction pathways and, ultimately, cellular responses.

Clinical significance

While the specific clinical significance of OR13G1 is not yet fully understood, olfactory receptors in general are believed to have roles in various diseases such as Parkinson's disease, Alzheimer's disease, and cancer.

See also

• Olfactory receptor
• G protein-coupled receptor
• Chromosome 1

References

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