OR4K13

OR4K13 is a gene that encodes a protein in humans. This protein is a member of the olfactory receptor family, a class of G protein-coupled receptors (GPCRs) that are involved in the detection of smell. The specific function of OR4K13 is not well understood, but it is believed to play a role in olfaction.

Structure

The OR4K13 gene is located on chromosome 11 in humans. It spans approximately 1 kilobase and consists of a single exon. The encoded protein is a member of the olfactory receptor family, which is the largest family of GPCRs. Like other olfactory receptors, OR4K13 is believed to have a seven-transmembrane domain structure, which is characteristic of GPCRs.

Function

The exact function of OR4K13 is not well understood. However, it is known that olfactory receptors, including OR4K13, are responsible for the detection of odor molecules. These receptors are located on the cilia of olfactory sensory neurons in the nose. When an odor molecule binds to an olfactory receptor, it triggers a signal transduction pathway that results in the perception of smell.

Clinical significance

While the specific role of OR4K13 in disease is not well understood, mutations in olfactory receptor genes have been associated with various disorders. For example, a reduced sense of smell (known as anosmia) can result from mutations in these genes. Further research is needed to determine the specific role of OR4K13 in health and disease.

See also

• Olfactory receptor
• G protein-coupled receptor
• Anosmia

References

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