OR5B2

OR5B2 is a gene that encodes a protein in humans. It is also known as Olfactory Receptor Family 5 Subfamily B Member 2. The OR5B2 gene is part of the olfactory receptor family, which is the largest gene family in the genome. The family members are G-protein coupled receptors that respond to smell and taste stimuli and are responsible for our sense of smell.

Function

The OR5B2 gene encodes a protein that is a member of the olfactory receptor family. These receptors are located in the olfactory epithelium in the nose. They interact with odorant molecules in the air, triggering a neuronal response that allows us to perceive smell. Each olfactory receptor gene is expressed in a unique small subset of olfactory receptor neurons in the nose.

Structure

The OR5B2 protein is a G protein-coupled receptor (GPCR), which is a type of protein that spans the cell membrane and communicates signals from outside the cell to inside the cell. GPCRs are involved in many different physiological functions, including sensory perception, immune response, and regulation of mood and behavior.

Clinical Significance

While the specific role of OR5B2 in disease is not well understood, olfactory receptors in general have been implicated in a variety of diseases, including Parkinson's disease, Alzheimer's disease, and certain types of cancer. Further research is needed to understand the specific role of OR5B2 in these and other diseases.

See Also

• Olfactory receptor
• G protein-coupled receptor
• Olfactory epithelium

References

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