OR1J4

OR1J4 is a gene that encodes a protein in humans. It is also known as Olfactory Receptor Family 1 Subfamily J Member 4. This gene is part of the olfactory receptor family, which is the largest gene family in the genome. The olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell.

Function

The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

Gene

The OR1J4 gene is located on chromosome 1, specifically on the long (q) arm of chromosome 1 at position 23.2, from base pair 159,687,063 to base pair 159,688,062.

Clinical significance

Variations in this gene can lead to differences in an individual's sense of smell. More research is needed to understand the specific roles and potential clinical significance of this gene.

See also

• Olfactory receptor
• G protein-coupled receptor
• Chromosome 1 (human)

References

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