Notch

Notch is a term used in various fields of study, including biology, genetics, and computer science. In biology, it refers to a family of proteins that play a key role in the development of organisms. In genetics, it refers to a gene that encodes these proteins. In computer science, it is the pseudonym of Markus Persson, a Swedish video game developer and founder of Mojang Studios.

Biology

In biology, the Notch signaling pathway is a highly conserved cell signaling system present in most multicellular organisms. Mammals possess four different notch receptors, referred to as NOTCH1, NOTCH2, NOTCH3, and NOTCH4. The notch receptor is a single-pass transmembrane receptor protein. It is a hetero-oligomer composed of a large extracellular portion, which associates in a calcium-dependent, non-covalent interaction with a smaller piece of the notch protein composed of a short extracellular region, a single transmembrane-pass, and a small intracellular region.

Genetics

In genetics, the Notch gene family encodes transmembrane receptors that play a key role in cell fate decisions. Mutations in these genes are associated with a variety of genetic disorders, including Alagille syndrome, spondylocostal dysostosis, and Adams-Oliver syndrome.

Computer Science

In computer science, "Notch" is the pseudonym of Markus Persson, a Swedish video game developer and founder of Mojang Studios. He is best known for creating the popular sandbox game Minecraft.

See also

• Notch signaling pathway
• Notch receptor
• Minecraft

References

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