IFNA8

IFNA8 is a protein that in humans is encoded by the IFNA8 gene. The protein encoded by this gene is a member of the interferon family. Interferons are proteins released by host cells in response to the presence of pathogens such as viruses, bacteria, parasites or tumor cells. They allow communication between cells to trigger the protective defenses of the immune system that eradicate pathogens or tumors.

Function

Interferons are produced by the cells of the immune system in response to challenges by foreign agents such as viruses, parasites and tumor cells. Interferon-alpha and interferon-beta are classified as type I interferons. They are produced when the immune system signals the body to defend itself against viral infections. IFNA8 is a type I interferon.

Clinical significance

Interferons have been recognized for their anti-viral effects and are used clinically to treat a number of viral conditions including hepatitis B, hepatitis C, human papillomavirus, and Kaposi's sarcoma. There is also evidence that they produce antitumor effects and thus may be used to treat various types of cancer.

See also

• Interferon
• Interferon type I
• IFNA

References

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External links

• IFNA8 at the US National Library of Medicine Medical Subject Headings (MeSH)

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