De novo

De novo is a Latin expression meaning "from the beginning", "afresh", "anew", "beginning again". In the context of biology and medicine, de novo implies events or processes that start from the beginning independent of any genetic influence.

Overview

In genetics, a de novo mutation is a mutation that neither parent possessed or transmitted. In this case, the mutation is present for the first time in one family member as a result of a mutation in a germ cell (egg or sperm) of one of the parents, or in the fertilized egg itself.

In medicine, de novo is also often used to refer to health conditions that occur spontaneously or for the first time in a family due to these types of genetic mutations.

De Novo in Genetics

In genetics, de novo mutations can occur in a germ cell of one of the parents or in the fertilized egg itself. These mutations can lead to genetic disorders in the offspring even if the parents do not have the disorder.

De Novo in Medicine

In medicine, de novo conditions are those that are not inherited from parents but occur spontaneously. These conditions can be caused by a variety of factors including environmental factors, lifestyle factors, and de novo genetic mutations.

See Also

• Genetics
• Mutation
• Genetic Disorders
• Medicine

References

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