Columbid alphaherpesvirus 1

Columbid alphaherpesvirus 1 (CoHV-1) is a species of virus in the genus Iltovirus within the family Herpesviridae. It is known to infect pigeons and doves, causing a disease commonly referred to as pigeon herpesvirus infection.

Virology

Columbid alphaherpesvirus 1 is a double-stranded DNA virus. Like other members of the Herpesviridae family, it has a characteristic icosahedral capsid surrounded by a lipid envelope. The genome of CoHV-1 is linear and approximately 150 kilobases in length, encoding a variety of proteins necessary for viral replication and pathogenesis.

Pathogenesis

CoHV-1 primarily infects Columbidae, which includes pigeons and doves. The virus is transmitted through direct contact with infected birds or through exposure to contaminated environments. Once inside the host, CoHV-1 targets epithelial cells and can establish a latent infection in the nervous system, similar to other herpesviruses.

Clinical signs of infection can vary but often include respiratory distress, conjunctivitis, and neurological symptoms. In some cases, the infection can be fatal, particularly in young or immunocompromised birds.

Diagnosis

Diagnosis of CoHV-1 infection is typically based on clinical signs and confirmed through laboratory testing. Techniques such as polymerase chain reaction (PCR) and virus isolation are commonly used to detect the presence of viral DNA or live virus in samples from affected birds.

Treatment and Control

There is no specific antiviral treatment for CoHV-1 infection in birds. Management of the disease focuses on supportive care and prevention of secondary infections. Vaccination strategies have been explored, but no widely available vaccine exists for CoHV-1.

Control measures include maintaining good hygiene and biosecurity practices to prevent the spread of the virus among bird populations. Quarantine of affected birds and disinfection of contaminated areas are also important strategies.

Also see

• Herpesviridae
• Iltovirus
• Pigeon circovirus
• Avian diseases

Herpesviridae
Herpesviridae virion
Taxonomy
Kingdom	Virus
Order	Herpesvirales
Family	Herpesviridae
Genera
Simplexvirus Varicellovirus Cytomegalovirus Roseolovirus Rhadinovirus Iltovirus Mardivirus Percavirus Scutavirus
Notable Species
Herpes simplex virus 1 (HSV-1) Herpes simplex virus 2 (HSV-2) Varicella zoster virus (VZV) Epstein–Barr virus (EBV) Cytomegalovirus (CMV) Human herpesvirus 6 (HHV-6) Human herpesvirus 7 (HHV-7) Kaposi's sarcoma-associated herpesvirus (KSHV)
Related Topics
Herpesvirus latency Herpesvirus infections Antiviral drugs Viral replication