CYP1A1

CYP1A1 is a gene that encodes the enzyme cytochrome P450 1A1. This enzyme is part of the cytochrome P450 superfamily of enzymes, which play a crucial role in the body's ability to process drugs, toxins, and other substances.

Function

The CYP1A1 gene provides instructions for making an enzyme that is found in the lining of the lungs and intestines. This enzyme, called cytochrome P450 1A1, is part of a large group of enzymes that help the body break down and get rid of certain drugs and toxins. Cytochrome P450 1A1 also helps process substances that are not normally found in the body, such as chemicals in tobacco smoke and certain types of food.

Genetic Variations

Certain variations of the CYP1A1 gene can affect how well the body is able to process certain substances. For example, some variations can make the enzyme less effective at breaking down certain drugs and toxins, which can increase the risk of certain health problems. Other variations can make the enzyme more effective, which can decrease the risk of these problems.

Health Impact

Research has shown that variations in the CYP1A1 gene can affect a person's risk of developing certain types of cancer, including lung cancer and colorectal cancer. However, more research is needed to fully understand the role of this gene in cancer development.

See Also

• Cytochrome P450
• Genetic Variation
• Lung Cancer
• Colorectal Cancer

References

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