4,5-DHP-DMT: Difference between revisions

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{{Short description|Chemical compound}}
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{{DISPLAYTITLE:4,5-DHP-DMT}}


'''4,5-DHP-DMT''' (4,5-dihydroxy-N,N-dimethyltryptamine) is a [[psychedelic]] compound belonging to the [[tryptamine]] class. It is structurally related to other tryptamines such as [[DMT]] (N,N-dimethyltryptamine) and [[psilocin]].
[[File:4,5-DHP-DMT.svg|thumb|right|Chemical structure of 4,5-DHP-DMT]]
 
'''4,5-DHP-DMT''' (4,5-dihydroxy-N,N-dimethyltryptamine) is a [[psychedelic]] compound belonging to the [[tryptamine]] class. It is structurally related to [[DMT]] (N,N-dimethyltryptamine), a well-known psychedelic substance. The compound is characterized by the presence of two hydroxyl groups at the 4 and 5 positions of the indole ring.


==Chemical Structure and Properties==
==Chemical Structure and Properties==
[[File:4,5-DHP-DMT.svg|Chemical structure of 4,5-DHP-DMT|thumb|right]]
4,5-DHP-DMT is a derivative of DMT, with the chemical formula C<sub>12</sub>H<sub>16</sub>N<sub>2</sub>O<sub>2</sub>. The addition of hydroxyl groups to the indole ring significantly alters its chemical properties compared to DMT. These modifications can affect the compound's [[solubility]], [[stability]], and [[pharmacokinetics]].
4,5-DHP-DMT is characterized by the presence of two hydroxyl groups at the 4 and 5 positions of the indole ring, which distinguishes it from other tryptamines. The chemical formula for 4,5-DHP-DMT is C12H16N2O2, and it has a molecular weight of 220.27 g/mol.


The presence of the hydroxyl groups makes 4,5-DHP-DMT more polar than its non-hydroxylated counterparts, potentially affecting its pharmacokinetics and interaction with biological systems.
==Synthesis==
The synthesis of 4,5-DHP-DMT involves the hydroxylation of the indole ring of DMT. This process can be achieved through various chemical reactions, including the use of oxidizing agents. The synthesis requires careful control of reaction conditions to ensure the selective addition of hydroxyl groups at the desired positions.


==Pharmacology==
==Pharmacology==
4,5-DHP-DMT is believed to act as a [[serotonin receptor]] agonist, similar to other psychedelic tryptamines. It likely interacts with the [[5-HT2A receptor]], which is thought to be responsible for the psychedelic effects of these compounds. However, detailed studies on its receptor binding profile and pharmacodynamics are limited.
The pharmacological effects of 4,5-DHP-DMT are not well-documented, but it is presumed to interact with [[serotonin receptors]] in a manner similar to other tryptamines. The presence of hydroxyl groups may influence its binding affinity and efficacy at these receptors, potentially altering its psychedelic effects.
 
==Effects==
The effects of 4,5-DHP-DMT are not well-documented in scientific literature. However, based on its structural similarity to other tryptamines, it may produce altered states of consciousness, visual and auditory hallucinations, and changes in perception and mood. The intensity and duration of these effects can vary depending on the dose and individual differences.


==Synthesis==
==Potential Effects==
The synthesis of 4,5-DHP-DMT involves the hydroxylation of DMT at the 4 and 5 positions. This can be achieved through various chemical reactions, but specific synthetic routes are not widely published in the literature.
While specific studies on 4,5-DHP-DMT are lacking, it is likely to produce effects similar to other tryptamines, such as [[hallucinations]], [[altered perception]], and changes in [[mood]] and [[thought]]. The exact nature and intensity of these effects would depend on the compound's pharmacokinetics and receptor interactions.


==Legal Status==
==Legal Status==
The legal status of 4,5-DHP-DMT varies by country. In many jurisdictions, it may be considered a controlled substance due to its structural similarity to other regulated tryptamines. Researchers and individuals interested in this compound should consult local regulations before handling or studying it.
The legal status of 4,5-DHP-DMT varies by country. In many jurisdictions, it may be considered a controlled substance due to its structural similarity to DMT. Researchers interested in studying this compound must comply with relevant regulations and obtain necessary approvals.


==Related Compounds==
==Research and Applications==
* [[DMT]]
Research on 4,5-DHP-DMT is limited, but it may offer insights into the structure-activity relationships of tryptamines. Understanding how modifications to the indole ring affect pharmacological properties could inform the development of new therapeutic agents targeting the [[central nervous system]].
* [[Psilocin]]
* [[Bufotenin]]
* [[5-MeO-DMT]]


==Related Pages==
==Related Pages==
* [[DMT]]
* [[Tryptamine]]
* [[Tryptamine]]
* [[Psychedelic drug]]
* [[Psychedelic drug]]

Latest revision as of 06:17, 5 March 2025

Chemical compound



Chemical structure of 4,5-DHP-DMT

4,5-DHP-DMT (4,5-dihydroxy-N,N-dimethyltryptamine) is a psychedelic compound belonging to the tryptamine class. It is structurally related to DMT (N,N-dimethyltryptamine), a well-known psychedelic substance. The compound is characterized by the presence of two hydroxyl groups at the 4 and 5 positions of the indole ring.

Chemical Structure and Properties[edit]

4,5-DHP-DMT is a derivative of DMT, with the chemical formula C12H16N2O2. The addition of hydroxyl groups to the indole ring significantly alters its chemical properties compared to DMT. These modifications can affect the compound's solubility, stability, and pharmacokinetics.

Synthesis[edit]

The synthesis of 4,5-DHP-DMT involves the hydroxylation of the indole ring of DMT. This process can be achieved through various chemical reactions, including the use of oxidizing agents. The synthesis requires careful control of reaction conditions to ensure the selective addition of hydroxyl groups at the desired positions.

Pharmacology[edit]

The pharmacological effects of 4,5-DHP-DMT are not well-documented, but it is presumed to interact with serotonin receptors in a manner similar to other tryptamines. The presence of hydroxyl groups may influence its binding affinity and efficacy at these receptors, potentially altering its psychedelic effects.

Potential Effects[edit]

While specific studies on 4,5-DHP-DMT are lacking, it is likely to produce effects similar to other tryptamines, such as hallucinations, altered perception, and changes in mood and thought. The exact nature and intensity of these effects would depend on the compound's pharmacokinetics and receptor interactions.

Legal Status[edit]

The legal status of 4,5-DHP-DMT varies by country. In many jurisdictions, it may be considered a controlled substance due to its structural similarity to DMT. Researchers interested in studying this compound must comply with relevant regulations and obtain necessary approvals.

Research and Applications[edit]

Research on 4,5-DHP-DMT is limited, but it may offer insights into the structure-activity relationships of tryptamines. Understanding how modifications to the indole ring affect pharmacological properties could inform the development of new therapeutic agents targeting the central nervous system.

Related Pages[edit]