Pyloric stenosis: Difference between revisions

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'''Pyloric stenosis''' is a condition that affects the [[gastrointestinal tract]] in infants. It is characterized by the narrowing of the [[pylorus]], the lower part of the stomach that connects to the [[small intestine]]. This condition can cause severe [[vomiting]], weight loss, and dehydration.
{{Short description|A condition affecting the gastrointestinal tract in infants}}


== Symptoms and signs ==
'''Pyloric stenosis''' is a condition that affects the gastrointestinal tract in infants, characterized by the narrowing of the pylorus, the opening from the stomach into the small intestine. This condition leads to severe projectile vomiting, dehydration, and weight loss in affected infants.
The most common symptom of pyloric stenosis is [[projectile vomiting]], which typically starts around three weeks of age. Other symptoms can include weight loss, dehydration, and changes in bowel movements. Infants with this condition may also appear to be constantly hungry.


== Causes ==
==Pathophysiology==
The exact cause of pyloric stenosis is unknown, but it is believed to be a combination of genetic and environmental factors. Some studies suggest that certain antibiotics taken during pregnancy or in the first weeks of a baby's life can increase the risk of developing this condition.
The pylorus is a muscular valve that regulates the passage of food from the stomach to the duodenum. In pyloric stenosis, the muscles of the pylorus become hypertrophied, leading to a narrowing of the pyloric channel. This hypertrophy obstructs gastric emptying, causing the stomach contents to be forcefully expelled.


== Diagnosis ==
==Epidemiology==
Diagnosis of pyloric stenosis involves a physical examination and medical history. The doctor may also order tests such as an [[ultrasound]] or a [[barium swallow]] to confirm the diagnosis.
Pyloric stenosis is more common in males than females, with a male-to-female ratio of approximately 4:1. It typically presents in infants between 2 to 8 weeks of age. The condition is more prevalent in first-born children and has a higher incidence in Caucasian populations.


== Treatment ==
==Clinical Presentation==
The primary treatment for pyloric stenosis is surgery, known as a [[pyloromyotomy]]. This procedure involves cutting the muscle of the pylorus to allow food to pass through more easily. Most infants recover quickly after surgery and have no long-term health effects.
Infants with pyloric stenosis often present with:
* Projectile vomiting: Non-bilious vomiting that occurs shortly after feeding.
* Dehydration: Due to loss of fluids from vomiting.
* Weight loss: Resulting from inadequate nutrition and fluid intake.
* Palpable "olive": A firm, mobile mass in the right upper quadrant of the abdomen, representing the hypertrophied pylorus.


== Epidemiology ==
==Diagnosis==
Pyloric stenosis is more common in males than in females, and it often runs in families. It is also more common in first-born children. The condition affects approximately 2 to 4 out of every 1,000 babies in the United States.
The diagnosis of pyloric stenosis is primarily clinical, supported by imaging studies.  


== See also ==
===Ultrasound===
[[Ultrasound]] is the preferred imaging modality, revealing a thickened pyloric muscle and elongated pyloric channel. The "target sign" or "doughnut sign" is often described on transverse imaging.
 
===Barium Swallow===
A [[barium swallow]] study may show a "string sign," indicating a narrowed pyloric channel.
 
==Management==
The definitive treatment for pyloric stenosis is surgical intervention.
 
===Pyloromyotomy===
The standard surgical procedure is a [[pyloromyotomy]], where the outer layer of the pylorus muscle is split, allowing the inner mucosa to bulge out and relieve the obstruction. This procedure can be performed via an open or laparoscopic approach.
 
===Preoperative Care===
Before surgery, it is crucial to correct dehydration and electrolyte imbalances. Intravenous fluids are administered to stabilize the infant.
 
==Prognosis==
With appropriate surgical treatment, the prognosis for infants with pyloric stenosis is excellent. Most infants recover fully and have no long-term complications.
 
==Related pages==
* [[Gastrointestinal tract]]
* [[Gastrointestinal tract]]
* [[Pylorus]]
* [[Infant vomiting]]
* [[Projectile vomiting]]
* [[Hypertrophy]]
* [[Pyloromyotomy]]
* [[Surgical procedures]]
 
[[Category:Gastrointestinal tract disorders]]
[[Category:Pediatric disorders]]
[[Category:Surgical procedures]]


{{stub}}
[[Category:Congenital disorders of digestive system]]
{{dictionary-stub1}}
[[Category:Pediatrics]]
== Pyloric_stenosis ==
<gallery>
File:Gray1046.svg|Diagram of the stomach showing the pylorus
File:Pyloric-stenosisLocal.jpg|Ultrasound image of pyloric stenosis
File:Pyloromyotomie.jpg|Surgical image of pyloromyotomy
File:PyloricStenosisHorizontal.jpg|Horizontal view of pyloric stenosis
File:Pylorusstenose.jpg|Image showing pylorus stenosis
File:Laparoscopic_Pyloromyotomy_scar,_6hrs_post-op.jpg|Laparoscopic pyloromyotomy scar, 6 hours post-operation
</gallery>

Revision as of 17:42, 18 February 2025

A condition affecting the gastrointestinal tract in infants


Pyloric stenosis is a condition that affects the gastrointestinal tract in infants, characterized by the narrowing of the pylorus, the opening from the stomach into the small intestine. This condition leads to severe projectile vomiting, dehydration, and weight loss in affected infants.

Pathophysiology

The pylorus is a muscular valve that regulates the passage of food from the stomach to the duodenum. In pyloric stenosis, the muscles of the pylorus become hypertrophied, leading to a narrowing of the pyloric channel. This hypertrophy obstructs gastric emptying, causing the stomach contents to be forcefully expelled.

Epidemiology

Pyloric stenosis is more common in males than females, with a male-to-female ratio of approximately 4:1. It typically presents in infants between 2 to 8 weeks of age. The condition is more prevalent in first-born children and has a higher incidence in Caucasian populations.

Clinical Presentation

Infants with pyloric stenosis often present with:

  • Projectile vomiting: Non-bilious vomiting that occurs shortly after feeding.
  • Dehydration: Due to loss of fluids from vomiting.
  • Weight loss: Resulting from inadequate nutrition and fluid intake.
  • Palpable "olive": A firm, mobile mass in the right upper quadrant of the abdomen, representing the hypertrophied pylorus.

Diagnosis

The diagnosis of pyloric stenosis is primarily clinical, supported by imaging studies.

Ultrasound

Ultrasound is the preferred imaging modality, revealing a thickened pyloric muscle and elongated pyloric channel. The "target sign" or "doughnut sign" is often described on transverse imaging.

Barium Swallow

A barium swallow study may show a "string sign," indicating a narrowed pyloric channel.

Management

The definitive treatment for pyloric stenosis is surgical intervention.

Pyloromyotomy

The standard surgical procedure is a pyloromyotomy, where the outer layer of the pylorus muscle is split, allowing the inner mucosa to bulge out and relieve the obstruction. This procedure can be performed via an open or laparoscopic approach.

Preoperative Care

Before surgery, it is crucial to correct dehydration and electrolyte imbalances. Intravenous fluids are administered to stabilize the infant.

Prognosis

With appropriate surgical treatment, the prognosis for infants with pyloric stenosis is excellent. Most infants recover fully and have no long-term complications.

Related pages