Intraductal papilloma: Difference between revisions

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'''Intraductal papilloma''' is a small, benign tumor that forms in a milk duct in the breast. These tumors are made of gland and fibrous tissue as well as blood vessels. They most commonly occur in women aged 35-55 years.
{{Short description|A benign breast condition involving the milk ducts}}


== Symptoms ==
'''Intraductal papilloma''' is a non-cancerous (benign) breast condition characterized by the growth of small, wart-like tumors in the milk ducts of the breast. These growths are typically found near the nipple and can cause nipple discharge or discomfort. While intraductal papillomas are benign, they can sometimes be associated with an increased risk of breast cancer.
The most common symptom of intraductal papilloma is nipple discharge, which is often clear or bloody. Other symptoms may include a lump in the breast or nipple and nipple inversion or retraction. In some cases, intraductal papilloma may cause no symptoms and may be discovered during a routine mammogram.


== Causes ==
==Pathophysiology==
The exact cause of intraductal papilloma is not known. However, it is believed to be related to changes in hormone levels, as these tumors are more common in women who are nearing menopause.
Intraductal papillomas are composed of fibrous tissue and blood vessels, and they develop within the milk ducts of the breast. These growths can occur singly (solitary papillomas) or in multiples (multiple papillomas). Solitary papillomas are usually found in the larger ducts near the nipple, while multiple papillomas tend to occur deeper within the breast tissue.


== Diagnosis ==
==Clinical Presentation==
Intraductal papilloma is usually diagnosed through a combination of physical examination, imaging tests such as mammography or ultrasound, and biopsy. The biopsy can be performed using fine-needle aspiration, core needle biopsy, or surgical biopsy.
Patients with intraductal papilloma may present with:
* Nipple discharge, which can be clear, serous, or bloody.
* A palpable lump near the nipple.
* Breast pain or tenderness.


== Treatment ==
The discharge is often spontaneous and may be the only symptom. In some cases, the papilloma may be detected during a routine [[mammography]] or [[breast ultrasound]].
The treatment for intraductal papilloma usually involves surgical removal of the tumor. In some cases, the entire affected milk duct may be removed. If the biopsy shows that the papilloma has atypical cells or is associated with a high risk of breast cancer, additional treatment such as radiation therapy or hormone therapy may be recommended.


== Prognosis ==
==Diagnosis==
The prognosis for intraductal papilloma is generally good. However, these tumors can sometimes be associated with a slightly increased risk of developing breast cancer.
The diagnosis of intraductal papilloma typically involves:
* [[Physical examination]]: A healthcare provider may feel a small lump near the nipple.
* Imaging studies: [[Mammography]] and [[ultrasound]] can help visualize the papilloma.
* [[Ductography]]: A specialized imaging technique where contrast dye is injected into the milk ducts to highlight abnormalities.
* [[Biopsy]]: A core needle biopsy or excisional biopsy may be performed to obtain a tissue sample for histological examination.


[[Category:Breast diseases]]
==Treatment==
[[Category:Benign neoplasms]]
The primary treatment for intraductal papilloma is surgical excision. This involves removing the papilloma and a small margin of surrounding tissue to ensure complete removal. Surgery is often recommended to alleviate symptoms and to rule out any associated malignancy.
[[Category:Endocrine neoplasms]]
 
==Prognosis==
The prognosis for individuals with intraductal papilloma is generally excellent, as these lesions are benign. However, regular follow-up is important, especially if there are multiple papillomas or if there is any atypical hyperplasia, as these conditions may increase the risk of developing breast cancer.
 
==Prevention and Risk Factors==
While there are no specific measures to prevent intraductal papilloma, awareness of breast changes and regular breast examinations can aid in early detection. Risk factors may include:
* Age: Most common in women aged 35-55.
* Hormonal factors: Estrogen exposure may play a role.


See also:
==Related pages==
* [[Breast cancer]]
* [[Breast cancer]]
* [[Mammography]]
* [[Mammography]]
* [[Breast ultrasound]]
* [[Biopsy]]
* [[Biopsy]]


{{stub}}
[[Category:Breast diseases]]
{{dictionary-stub1}}
<gallery>
File:Intraductal_papilloma_histopathology_(3)_p63.JPG|Intraductal papilloma histopathology (p63 stain)
File:Intraductal_papilloma_histopathology_(1).jpg|Intraductal papilloma histopathology
File:Intraductal_papilloma_histopathology_(2)_smooth_muscle_actin.JPG|Intraductal papilloma histopathology (smooth muscle actin stain)
File:Ultrasound_12070I26_intraductal_papilloma_nevit.jpg|Ultrasound of intraductal papilloma
File:Ultrasound_12070I33_intraductal_papilloma_nevit.jpg|Ultrasound of intraductal papilloma
File:Ultrasound_12070I40_intraductal_papilloma_nevit.jpg|Ultrasound of intraductal papilloma
File:Ultrasound_12070I6_intraductal_papilloma_nevit.jpg|Ultrasound of intraductal papilloma
File:Ultrasound_12070I25_intraductal_papilloma_nevit.jpg|Ultrasound of intraductal papilloma
File:Ultrasound_12070I12_intraductal_papilloma_nevit.jpg|Ultrasound of intraductal papilloma
</gallery>

Revision as of 17:33, 18 February 2025

A benign breast condition involving the milk ducts


Intraductal papilloma is a non-cancerous (benign) breast condition characterized by the growth of small, wart-like tumors in the milk ducts of the breast. These growths are typically found near the nipple and can cause nipple discharge or discomfort. While intraductal papillomas are benign, they can sometimes be associated with an increased risk of breast cancer.

Pathophysiology

Intraductal papillomas are composed of fibrous tissue and blood vessels, and they develop within the milk ducts of the breast. These growths can occur singly (solitary papillomas) or in multiples (multiple papillomas). Solitary papillomas are usually found in the larger ducts near the nipple, while multiple papillomas tend to occur deeper within the breast tissue.

Clinical Presentation

Patients with intraductal papilloma may present with:

  • Nipple discharge, which can be clear, serous, or bloody.
  • A palpable lump near the nipple.
  • Breast pain or tenderness.

The discharge is often spontaneous and may be the only symptom. In some cases, the papilloma may be detected during a routine mammography or breast ultrasound.

Diagnosis

The diagnosis of intraductal papilloma typically involves:

  • Physical examination: A healthcare provider may feel a small lump near the nipple.
  • Imaging studies: Mammography and ultrasound can help visualize the papilloma.
  • Ductography: A specialized imaging technique where contrast dye is injected into the milk ducts to highlight abnormalities.
  • Biopsy: A core needle biopsy or excisional biopsy may be performed to obtain a tissue sample for histological examination.

Treatment

The primary treatment for intraductal papilloma is surgical excision. This involves removing the papilloma and a small margin of surrounding tissue to ensure complete removal. Surgery is often recommended to alleviate symptoms and to rule out any associated malignancy.

Prognosis

The prognosis for individuals with intraductal papilloma is generally excellent, as these lesions are benign. However, regular follow-up is important, especially if there are multiple papillomas or if there is any atypical hyperplasia, as these conditions may increase the risk of developing breast cancer.

Prevention and Risk Factors

While there are no specific measures to prevent intraductal papilloma, awareness of breast changes and regular breast examinations can aid in early detection. Risk factors may include:

  • Age: Most common in women aged 35-55.
  • Hormonal factors: Estrogen exposure may play a role.

Related pages