Levodropropizine: Difference between revisions

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'''Levodropropizine''' is a non-opioid [[antitussive]] agent, used primarily for the treatment of [[cough]]. It is an [[antagonist]] of the [[histamine]] H1 receptor and an inhibitor of the [[tachykinin]] NK1 receptor. Levodropropizine is marketed under various brand names worldwide.
== Levodropropizine ==


==Pharmacology==
[[File:Levopront_levodropropizine5.jpg|thumb|right|Levodropropizine syrup]]
Levodropropizine works by reducing the activity of the [[cough reflex]] and reducing the need to cough. It is considered a peripheral antitussive, as it does not act on the [[central nervous system]] but on the [[sensory nerve endings]] in the [[respiratory tract]].


==Clinical Use==
'''Levodropropizine''' is a [[cough suppressant]] medication used primarily in the treatment of [[non-productive cough]]. It is a non-opioid antitussive agent that acts peripherally to reduce the cough reflex.
Levodropropizine is used for the treatment of productive and non-productive cough. It is often used when the cough is not being controlled by other treatments, or when other treatments are not suitable. It is typically administered in [[syrup]] form.


==Side Effects==
== Pharmacology ==
Common side effects of Levodropropizine include [[gastrointestinal]] disturbances, [[headache]], [[dizziness]], and [[rash]]. In rare cases, it can cause [[hypersensitivity]] reactions.
Levodropropizine works by inhibiting the release of [[neurotransmitters]] involved in the cough reflex. Unlike opioid cough suppressants, it does not act on the central nervous system, which reduces the risk of [[sedation]] and [[addiction]].


==Contraindications==
=== Mechanism of Action ===
Levodropropizine is contraindicated in patients with known hypersensitivity to the drug or any of its components. It should be used with caution in patients with severe [[liver disease]] or [[kidney disease]].
Levodropropizine acts on the peripheral nervous system by modulating the activity of [[sensory neurons]] in the respiratory tract. It reduces the sensitivity of the cough receptors, thereby decreasing the frequency and intensity of coughing.


==Interactions==
== Clinical Use ==
Levodropropizine may interact with other drugs that depress the [[central nervous system]], including [[alcohol]], [[barbiturates]], and [[benzodiazepines]].
Levodropropizine is indicated for the symptomatic treatment of [[dry cough]] in adults and children. It is often preferred in patients who are sensitive to the sedative effects of opioid-based cough suppressants.


==References==
=== Dosage and Administration ===
<references />
The typical dosage of levodropropizine for adults is 60 mg taken orally up to three times a day. For children, the dosage is adjusted based on body weight. It is important to follow the prescribed dosage to avoid potential side effects.
 
== Side Effects ==
Common side effects of levodropropizine include [[nausea]], [[dizziness]], and [[gastrointestinal discomfort]]. Rarely, it may cause [[allergic reactions]] such as [[rash]] or [[itching]].
 
== Contraindications ==
Levodropropizine is contraindicated in patients with known hypersensitivity to the drug. It should be used with caution in patients with [[renal impairment]] or [[liver disease]].
 
== Related Pages ==
* [[Cough suppressant]]
* [[Non-productive cough]]
* [[Peripheral nervous system]]
 
{{Antitussives}}


[[Category:Antitussives]]
[[Category:Antitussives]]
[[Category:Pharmacology]]
[[Category:Respiratory system drugs]]
[[Category:Medicine]]
 
{{medicine-stub}}

Latest revision as of 16:25, 16 February 2025

Levodropropizine[edit]

Levodropropizine syrup

Levodropropizine is a cough suppressant medication used primarily in the treatment of non-productive cough. It is a non-opioid antitussive agent that acts peripherally to reduce the cough reflex.

Pharmacology[edit]

Levodropropizine works by inhibiting the release of neurotransmitters involved in the cough reflex. Unlike opioid cough suppressants, it does not act on the central nervous system, which reduces the risk of sedation and addiction.

Mechanism of Action[edit]

Levodropropizine acts on the peripheral nervous system by modulating the activity of sensory neurons in the respiratory tract. It reduces the sensitivity of the cough receptors, thereby decreasing the frequency and intensity of coughing.

Clinical Use[edit]

Levodropropizine is indicated for the symptomatic treatment of dry cough in adults and children. It is often preferred in patients who are sensitive to the sedative effects of opioid-based cough suppressants.

Dosage and Administration[edit]

The typical dosage of levodropropizine for adults is 60 mg taken orally up to three times a day. For children, the dosage is adjusted based on body weight. It is important to follow the prescribed dosage to avoid potential side effects.

Side Effects[edit]

Common side effects of levodropropizine include nausea, dizziness, and gastrointestinal discomfort. Rarely, it may cause allergic reactions such as rash or itching.

Contraindications[edit]

Levodropropizine is contraindicated in patients with known hypersensitivity to the drug. It should be used with caution in patients with renal impairment or liver disease.

Related Pages[edit]

Template:Antitussives