Methylenedioxyphencyclidine: Difference between revisions

Latest revision as of 05:55, 16 February 2025

Methylenedioxyphencyclidine[edit]

Methylenedioxyphencyclidine (MDPCP) is a synthetic dissociative drug that belongs to the arylcyclohexylamine class. It is chemically related to phencyclidine (PCP) and is known for its psychoactive effects, which include hallucinations, altered perceptions, and dissociation.

Chemical Structure[edit]

MDPCP is characterized by the presence of a methylenedioxy group attached to the phenyl ring of the phencyclidine structure. This modification is similar to that found in other psychoactive compounds such as 3,4-methylenedioxyamphetamine (MDA) and 3,4-methylenedioxymethamphetamine (MDMA). The chemical structure of MDPCP can be represented as 1-(1-(3,4-methylenedioxyphenyl)cyclohexyl)piperidine.

Pharmacology[edit]

MDPCP acts primarily as an NMDA receptor antagonist, similar to PCP and ketamine. By blocking the NMDA receptor, MDPCP disrupts the normal functioning of the glutamate neurotransmitter system, leading to its dissociative effects. Users may experience a sense of detachment from their body and environment, as well as visual and auditory hallucinations.

Effects and Risks[edit]

The effects of MDPCP are dose-dependent and can vary significantly between individuals. Common effects include:

Dissociation and depersonalization
Euphoria
Altered sensory perceptions
Hallucinations

However, MDPCP also carries significant risks, including:

Neurotoxicity
Psychosis
Addiction potential
Cardiovascular complications

Legal Status[edit]

Due to its structural similarity to PCP and its potential for abuse, MDPCP is classified as a controlled substance in many countries. It is illegal to manufacture, possess, or distribute MDPCP without proper authorization.

Related Compounds[edit]

MDPCP is part of a broader class of dissociative anesthetics, which includes:

Related Pages[edit]

@@ Line 1: / Line 1: @@
-'''Methylenedioxyphencyclidine''' ('''MDPC''') is a [[psychoactive drug]] and [[research chemical]] of the [[arylcyclohexylamine]] class that has been sold online as a [[designer drug]]. It is an analog of [[phencyclidine]] (PCP) where the aromatic phenyl ring has been replaced by a [[benzodioxole]] ring.
+== Methylenedioxyphencyclidine ==
-==Chemistry==
+[[File:MDPCP_structure.png|thumb|right|Chemical structure of Methylenedioxyphencyclidine]]
-MDPC is an [[arylcyclohexylamine]] in the same family as [[phencyclidine]] (PCP) and [[ketamine]]. The structure of MDPC includes a [[phenyl]] ring bonded to an amino group (NH2) through a cyclohexane ring. An additional [[benzodioxole]] ring is bonded to the same carbon location where PCP contains a phenyl ring.
-==Pharmacology==
+'''Methylenedioxyphencyclidine''' (MDPCP) is a synthetic dissociative drug that belongs to the arylcyclohexylamine class. It is chemically related to [[phencyclidine]] (PCP) and is known for its psychoactive effects, which include hallucinations, altered perceptions, and dissociation.
-The pharmacological effects of MDPC are not well-studied. However, it is known to act as an [[NMDA receptor antagonist]]. NMDA receptors allow for electrical signals to pass between neurons in the brain and spinal column; for the signals to pass, the receptor must be open. Dissociatives close the NMDA receptors by blocking them. This disconnection of neurons leads to loss of feeling, difficulty moving, and eventually this substance can cause an [[out-of-body experience]].
-==Effects==
+== Chemical Structure ==
-The effects of MDPC can vary greatly depending on the dose taken. At lower doses, it can produce mild changes in perception, mood, and thought. At higher doses, it can lead to a state of complete dissociation from one's body and surroundings. This is similar to the effects of other [[dissociative]] drugs such as [[ketamine]], [[DXM]], and [[nitrous oxide]].
-==Legal Status==
+MDPCP is characterized by the presence of a methylenedioxy group attached to the phenyl ring of the phencyclidine structure. This modification is similar to that found in other psychoactive compounds such as [[3,4-methylenedioxyamphetamine]] (MDA) and [[3,4-methylenedioxymethamphetamine]] (MDMA). The chemical structure of MDPCP can be represented as 1-(1-(3,4-methylenedioxyphenyl)cyclohexyl)piperidine.
-The legal status of MDPC varies by country. In some countries, it is a controlled substance, while in others it is completely legal. It is important to check the legal status in your country before purchasing or using this substance.
+== Pharmacology ==
+MDPCP acts primarily as an [[NMDA receptor antagonist]], similar to PCP and [[ketamine]]. By blocking the NMDA receptor, MDPCP disrupts the normal functioning of the [[glutamate]] neurotransmitter system, leading to its dissociative effects. Users may experience a sense of detachment from their body and environment, as well as visual and auditory hallucinations.
+== Effects and Risks ==
+The effects of MDPCP are dose-dependent and can vary significantly between individuals. Common effects include:
+* Dissociation and depersonalization
+* Euphoria
+* Altered sensory perceptions
+* Hallucinations
+However, MDPCP also carries significant risks, including:
+* [[Neurotoxicity]]
+* [[Psychosis]]
+* [[Addiction]] potential
+* [[Cardiovascular]] complications
+== Legal Status ==
+Due to its structural similarity to PCP and its potential for abuse, MDPCP is classified as a controlled substance in many countries. It is illegal to manufacture, possess, or distribute MDPCP without proper authorization.
+== Related Compounds ==
+MDPCP is part of a broader class of dissociative anesthetics, which includes:
+* [[Phencyclidine]] (PCP)
+* [[Ketamine]]
+* [[Dextromethorphan]] (DXM)
+== Related Pages ==
-==See Also==
 * [[Phencyclidine]]
-* [[Ketamine]]
+* [[Dissociative drug]]
-* [[Dissociative]]
 * [[NMDA receptor antagonist]]
+* [[Psychoactive drug]]
-==References==
+[[Category:Dissociative drugs]]
-<references />
-[[Category:Psychoactive drugs]]
-[[Category:Research chemicals]]
 [[Category:Arylcyclohexylamines]]
-[[Category:Dissociatives]]
-[[Category:NMDA receptor antagonists]]
-{{pharmacology-stub}}