Adermatoglyphia: Difference between revisions
CSV import |
CSV import Tags: mobile edit mobile web edit |
||
| Line 2: | Line 2: | ||
{{Use dmy dates|date=October 2023}} | {{Use dmy dates|date=October 2023}} | ||
== Adermatoglyphia == | |||
[[File:Autosomal dominant - en.svg|thumb|right|Diagram of autosomal dominant inheritance]] | |||
[[ | '''Adermatoglyphia''' is a rare genetic disorder characterized by the absence of [[dermatoglyphics]], which are the ridges on the skin of the fingers, palms, toes, and soles. This condition is often referred to as "immigration delay disease" because individuals with adermatoglyphia lack fingerprints, which can complicate identity verification processes. | ||
== Genetics == | |||
Adermatoglyphia is inherited in an [[autosomal dominant]] pattern, meaning that a single copy of the altered gene in each cell is sufficient to cause the disorder. The condition is associated with mutations in the [[SMARCAD1]] gene, which plays a role in the development of skin ridges during embryonic development. | |||
== Clinical Features == | |||
Individuals with adermatoglyphia typically have: | Individuals with adermatoglyphia typically have: | ||
* Absence of fingerprints | * Absence of fingerprints | ||
* Normal | * Normal sweat gland function | ||
* No | * No other significant skin abnormalities | ||
The lack of fingerprints is the primary feature, and there are usually no other health issues associated with the condition. | The lack of fingerprints is the primary clinical feature, and there are usually no other health issues associated with the condition. | ||
==Diagnosis== | == Diagnosis == | ||
Diagnosis of adermatoglyphia is primarily based on the clinical observation of absent fingerprints. Genetic testing can confirm the presence of mutations in the SMARCAD1 gene. Family history can also provide clues, as the condition is inherited in an autosomal dominant manner. | |||
== | == Management == | ||
==Related pages== | There is no treatment required for adermatoglyphia, as it does not cause any health problems. Management focuses on addressing the practical issues related to the absence of fingerprints, such as difficulties with biometric identification. | ||
== Related pages == | |||
* [[Dermatoglyphics]] | * [[Dermatoglyphics]] | ||
* [[Genetic disorder]] | * [[Genetic disorder]] | ||
* [[Autosomal dominant]] | * [[Autosomal dominant]] | ||
[[Category:Genetic disorders]] | [[Category:Genetic disorders]] | ||
[[Category:Dermatology]] | [[Category:Dermatology]] | ||
Revision as of 05:40, 16 February 2025
A rare genetic disorder affecting fingerprints
Adermatoglyphia
Adermatoglyphia is a rare genetic disorder characterized by the absence of dermatoglyphics, which are the ridges on the skin of the fingers, palms, toes, and soles. This condition is often referred to as "immigration delay disease" because individuals with adermatoglyphia lack fingerprints, which can complicate identity verification processes.
Genetics
Adermatoglyphia is inherited in an autosomal dominant pattern, meaning that a single copy of the altered gene in each cell is sufficient to cause the disorder. The condition is associated with mutations in the SMARCAD1 gene, which plays a role in the development of skin ridges during embryonic development.
Clinical Features
Individuals with adermatoglyphia typically have:
- Absence of fingerprints
- Normal sweat gland function
- No other significant skin abnormalities
The lack of fingerprints is the primary clinical feature, and there are usually no other health issues associated with the condition.
Diagnosis
Diagnosis of adermatoglyphia is primarily based on the clinical observation of absent fingerprints. Genetic testing can confirm the presence of mutations in the SMARCAD1 gene. Family history can also provide clues, as the condition is inherited in an autosomal dominant manner.
Management
There is no treatment required for adermatoglyphia, as it does not cause any health problems. Management focuses on addressing the practical issues related to the absence of fingerprints, such as difficulties with biometric identification.
