MAM-2201: Difference between revisions

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'''MAM-2201''' is a [[drug]] that is a [[synthetic cannabinoid]] featuring an [[alkyl]] side chain. It is a full [[agonist]] for the [[CB1 receptor]] and [[CB2 receptor]]. MAM-2201 is part of a series of [[JWH-018]] [[amide]] derivatives and was originally developed by the pharmaceutical company [[Organon International]].
== MAM-2201 ==


==Chemistry==
[[File:MAM-2201_structure.png|thumb|right|Chemical structure of MAM-2201]]
MAM-2201 is a synthetic cannabinoid that is derived from JWH-018. It is an amide derivative of JWH-018, which means it has an amide group (-CONH2) attached to the pentyl chain of JWH-018. The chemical formula of MAM-2201 is C25H24FNO.


==Pharmacology==
'''MAM-2201''' is a synthetic cannabinoid that acts as a potent agonist of the [[cannabinoid receptor]]s. It is a member of the [[indole]] family of synthetic cannabinoids and is structurally related to other compounds such as [[JWH-018]] and [[AM-2201]].
MAM-2201 is a full agonist for the CB1 and CB2 receptors. The CB1 receptor is primarily located in the brain and affects mood, appetite, and pain sensation. The CB2 receptor is primarily found in the immune system and affects inflammation and pain.


==Effects==
=== Chemical Properties ===
The effects of MAM-2201 are similar to those of other synthetic cannabinoids and include [[euphoria]], [[relaxation]], and [[altered perception]]. However, MAM-2201 is more potent than JWH-018, and its effects can be unpredictable and potentially harmful.
MAM-2201 is chemically known as 1-(5-fluoropentyl)-3-(4-methyl-1-naphthoyl)indole. It is a fluorinated derivative of AM-2201, with the addition of a methyl group on the naphthoyl ring. This modification enhances its binding affinity to the [[CB1 receptor|CB1]] and [[CB2 receptor|CB2]] receptors, making it a highly potent synthetic cannabinoid.


==Legal Status==
=== Pharmacology ===
MAM-2201 is illegal in many countries, including the United States, where it is classified as a [[Schedule I drug]]. It is also illegal in the United Kingdom, where it is classified as a Class B drug.
MAM-2201 acts as a full agonist at the CB1 and CB2 receptors, which are part of the [[endocannabinoid system]]. These receptors are involved in a variety of physiological processes including pain sensation, mood, and memory. The activation of these receptors by MAM-2201 can lead to effects similar to those of [[tetrahydrocannabinol]] (THC), the active component of [[cannabis]].


==See Also==
=== Effects and Usage ===
The effects of MAM-2201 are similar to those of other synthetic cannabinoids and can include euphoria, relaxation, altered perception, and increased appetite. However, due to its high potency, it can also cause adverse effects such as anxiety, paranoia, and tachycardia. MAM-2201 has been used recreationally, often sprayed onto herbal mixtures and sold as "[[spice (drug)|spice]]" or "[[K2 (drug)|K2]]."
 
=== Legal Status ===
Due to its potential for abuse and lack of medical use, MAM-2201 has been classified as a controlled substance in many countries. It is often included in legislation targeting synthetic cannabinoids and "designer drugs."
 
== Related Pages ==
* [[Synthetic cannabinoids]]
* [[Cannabinoid receptor]]
* [[Endocannabinoid system]]
* [[JWH-018]]
* [[JWH-018]]
* [[Synthetic cannabinoids]]
* [[AM-2201]]
* [[CB1 receptor]]
* [[CB2 receptor]]


[[Category:Drugs]]
[[Category:Synthetic cannabinoids]]
[[Category:Synthetic cannabinoids]]
[[Category:CB1 receptor agonists]]
[[Category:CB2 receptor agonists]]
{{stub}}

Latest revision as of 11:33, 15 February 2025

MAM-2201[edit]

File:MAM-2201 structure.png
Chemical structure of MAM-2201

MAM-2201 is a synthetic cannabinoid that acts as a potent agonist of the cannabinoid receptors. It is a member of the indole family of synthetic cannabinoids and is structurally related to other compounds such as JWH-018 and AM-2201.

Chemical Properties[edit]

MAM-2201 is chemically known as 1-(5-fluoropentyl)-3-(4-methyl-1-naphthoyl)indole. It is a fluorinated derivative of AM-2201, with the addition of a methyl group on the naphthoyl ring. This modification enhances its binding affinity to the CB1 and CB2 receptors, making it a highly potent synthetic cannabinoid.

Pharmacology[edit]

MAM-2201 acts as a full agonist at the CB1 and CB2 receptors, which are part of the endocannabinoid system. These receptors are involved in a variety of physiological processes including pain sensation, mood, and memory. The activation of these receptors by MAM-2201 can lead to effects similar to those of tetrahydrocannabinol (THC), the active component of cannabis.

Effects and Usage[edit]

The effects of MAM-2201 are similar to those of other synthetic cannabinoids and can include euphoria, relaxation, altered perception, and increased appetite. However, due to its high potency, it can also cause adverse effects such as anxiety, paranoia, and tachycardia. MAM-2201 has been used recreationally, often sprayed onto herbal mixtures and sold as "spice" or "K2."

Legal Status[edit]

Due to its potential for abuse and lack of medical use, MAM-2201 has been classified as a controlled substance in many countries. It is often included in legislation targeting synthetic cannabinoids and "designer drugs."

Related Pages[edit]