Deoxyribose: Difference between revisions

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'''Deoxyribose''' is a [[monosaccharide]] (simple sugar) that is derived from [[ribose]] by the replacement of a [[hydroxyl]] group by [[hydrogen]]. It is an essential component of [[Deoxyribonucleic acid|DNA]], where it forms the backbone of the DNA structure.
== Deoxyribose ==
 
[[File:Deoxyribose_forms.svg|thumb|right|Structural forms of deoxyribose]]
 
'''Deoxyribose''' is a monosaccharide with the idealized formula H_(C=O)_(CH_)__OH. Its name indicates that it is a deoxy sugar, meaning that it is derived from the sugar [[ribose]] by the loss of an oxygen atom. Deoxyribose is most notable for its role in the structure of [[deoxyribonucleic acid]] (DNA), where it alternates with phosphate groups to form the "backbone" of the DNA polymer and binds to [[nitrogenous bases]].


== Structure ==
== Structure ==
Deoxyribose is a [[pentose]] sugar, meaning it is composed of five carbon atoms. It has the chemical formula C5H10O4. The structure of deoxyribose differs from ribose in that one of the hydroxyl (OH) groups found in ribose is replaced by a hydrogen (H) in deoxyribose.


== Role in DNA ==
Deoxyribose is a five-carbon sugar, or [[pentose]], with the chemical formula C_H__O_. It exists in several isomeric forms, including the open-chain form and the ring form. In the ring form, deoxyribose can exist as a furanose, which is a five-membered ring structure. The most common form of deoxyribose in DNA is the _-D-2-deoxyribofuranose.
In DNA, deoxyribose is connected to a [[phosphate]] group to form the backbone of the DNA double helix. The deoxyribose and phosphate molecules alternate to create the backbone, with the nitrogenous bases ([[adenine]], [[thymine]], [[cytosine]], and [[guanine]]) attached to the deoxyribose.
 
== Biological Role ==
 
Deoxyribose is a crucial component of DNA, which is the molecule responsible for storing and transmitting genetic information in all living organisms. In DNA, deoxyribose is linked to a phosphate group and a nitrogenous base to form a nucleotide. These nucleotides are the building blocks of DNA strands. The sequence of nucleotides in DNA encodes the genetic instructions used in the development and functioning of all known living organisms and many viruses.


== Synthesis ==
== Synthesis ==
Deoxyribose is synthesized in the body through a process called the [[Pentose phosphate pathway]]. This pathway also produces [[NADPH]] and ribose-5-phosphate, which are important for [[fatty acid synthesis]] and the synthesis of nucleotides and nucleic acids, respectively.


== See also ==
Deoxyribose is synthesized in cells from ribose 5-phosphate, a product of the [[pentose phosphate pathway]]. The enzyme ribonucleotide reductase catalyzes the reduction of ribose to deoxyribose, which is then incorporated into DNA.
 
== Related Compounds ==
 
Deoxyribose is closely related to [[ribose]], which is the sugar component of [[ribonucleic acid]] (RNA). The key difference between ribose and deoxyribose is the presence of a hydroxyl group on the 2' carbon in ribose, which is replaced by a hydrogen atom in deoxyribose.
 
== Related Pages ==
 
* [[Ribose]]
* [[Ribose]]
* [[DNA]]
* [[DNA]]
* [[RNA]]
* [[Nucleotide]]
* [[Nucleotide]]
* [[Pentose phosphate pathway]]
* [[Pentose phosphate pathway]]
== References ==
<references />
{{stub}}


[[Category:Monosaccharides]]
[[Category:Monosaccharides]]
[[Category:DNA]]
[[Category:DNA]]
[[Category:Nucleotides]]
[[Category:Biochemistry]]
{{dictionary-stub1}}

Latest revision as of 11:02, 15 February 2025

Deoxyribose[edit]

File:Deoxyribose forms.svg
Structural forms of deoxyribose

Deoxyribose is a monosaccharide with the idealized formula H_(C=O)_(CH_)__OH. Its name indicates that it is a deoxy sugar, meaning that it is derived from the sugar ribose by the loss of an oxygen atom. Deoxyribose is most notable for its role in the structure of deoxyribonucleic acid (DNA), where it alternates with phosphate groups to form the "backbone" of the DNA polymer and binds to nitrogenous bases.

Structure[edit]

Deoxyribose is a five-carbon sugar, or pentose, with the chemical formula C_H__O_. It exists in several isomeric forms, including the open-chain form and the ring form. In the ring form, deoxyribose can exist as a furanose, which is a five-membered ring structure. The most common form of deoxyribose in DNA is the _-D-2-deoxyribofuranose.

Biological Role[edit]

Deoxyribose is a crucial component of DNA, which is the molecule responsible for storing and transmitting genetic information in all living organisms. In DNA, deoxyribose is linked to a phosphate group and a nitrogenous base to form a nucleotide. These nucleotides are the building blocks of DNA strands. The sequence of nucleotides in DNA encodes the genetic instructions used in the development and functioning of all known living organisms and many viruses.

Synthesis[edit]

Deoxyribose is synthesized in cells from ribose 5-phosphate, a product of the pentose phosphate pathway. The enzyme ribonucleotide reductase catalyzes the reduction of ribose to deoxyribose, which is then incorporated into DNA.

Related Compounds[edit]

Deoxyribose is closely related to ribose, which is the sugar component of ribonucleic acid (RNA). The key difference between ribose and deoxyribose is the presence of a hydroxyl group on the 2' carbon in ribose, which is replaced by a hydrogen atom in deoxyribose.

Related Pages[edit]