3-HO-PCP: Difference between revisions
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== 3-HO-PCP == | |||
[[File:3-HO-PCP.svg|thumb|right|Chemical structure of 3-HO-PCP]] | |||
3-HO-PCP | |||
'''3-HO-PCP''' (3-Hydroxyphencyclidine) is a [[dissociative]] [[anesthetic]] of the [[arylcyclohexylamine]] class. It is a derivative of [[phencyclidine]] (PCP) and is known for its potent [[NMDA receptor]] antagonistic properties. | |||
== | === Chemical Structure === | ||
3-HO-PCP is chemically related to PCP, with the addition of a hydroxyl group at the third position of the phenyl ring. This modification alters its pharmacological profile, potentially affecting its potency and duration of action. | |||
=== Pharmacology === | |||
3-HO-PCP acts primarily as an antagonist at the NMDA receptor, a type of [[glutamate receptor]] in the brain. This action is responsible for its dissociative effects, which can include [[hallucinations]], [[analgesia]], and [[anesthesia]]. | |||
== | === Effects === | ||
The effects of 3-HO-PCP are similar to those of other dissociatives, such as [[ketamine]] and PCP. Users may experience altered perceptions of reality, changes in sensory perception, and a sense of detachment from the environment and self. The compound can also produce [[euphoria]] and [[sedation]]. | |||
== | === Risks and Safety === | ||
3-HO-PCP | As with other dissociative anesthetics, 3-HO-PCP carries risks of [[neurotoxicity]], [[psychosis]], and [[addiction]]. It is important to approach its use with caution, particularly due to its potency and the potential for unpredictable effects. | ||
== Related pages == | |||
==Related pages== | |||
* [[Phencyclidine]] | * [[Phencyclidine]] | ||
* [[Ketamine]] | * [[Ketamine]] | ||
* [[Dissociative drug]] | * [[Dissociative drug]] | ||
* [[NMDA receptor antagonist]] | |||
[[Category:Dissociative drugs]] | [[Category:Dissociative drugs]] | ||
[[Category:Arylcyclohexylamines]] | [[Category:Arylcyclohexylamines]] | ||
Latest revision as of 04:03, 13 February 2025
3-HO-PCP[edit]

3-HO-PCP (3-Hydroxyphencyclidine) is a dissociative anesthetic of the arylcyclohexylamine class. It is a derivative of phencyclidine (PCP) and is known for its potent NMDA receptor antagonistic properties.
Chemical Structure[edit]
3-HO-PCP is chemically related to PCP, with the addition of a hydroxyl group at the third position of the phenyl ring. This modification alters its pharmacological profile, potentially affecting its potency and duration of action.
Pharmacology[edit]
3-HO-PCP acts primarily as an antagonist at the NMDA receptor, a type of glutamate receptor in the brain. This action is responsible for its dissociative effects, which can include hallucinations, analgesia, and anesthesia.
Effects[edit]
The effects of 3-HO-PCP are similar to those of other dissociatives, such as ketamine and PCP. Users may experience altered perceptions of reality, changes in sensory perception, and a sense of detachment from the environment and self. The compound can also produce euphoria and sedation.
Risks and Safety[edit]
As with other dissociative anesthetics, 3-HO-PCP carries risks of neurotoxicity, psychosis, and addiction. It is important to approach its use with caution, particularly due to its potency and the potential for unpredictable effects.