Adie syndrome: Difference between revisions
CSV import |
CSV import |
||
| Line 1: | Line 1: | ||
{{Short description|A neurological disorder affecting the pupil | {{Short description|A neurological disorder affecting the pupil of the eye}} | ||
{{Use dmy dates|date=October 2023}} | {{Use dmy dates|date=October 2023}} | ||
'''Adie syndrome''', also known as '''Adie's tonic pupil''', is a neurological disorder characterized by a pupil that is larger than normal and reacts slowly to light. It is often associated with absent or diminished deep tendon reflexes | '''Adie syndrome''', also known as '''Adie's tonic pupil''', is a neurological disorder characterized by a pupil that is larger than normal and reacts slowly to light. It is often associated with absent or diminished deep tendon reflexes. The condition is named after the British neurologist William John Adie. | ||
==Signs and symptoms== | ==Signs and symptoms== | ||
The primary | [[File:Adies.png|thumb|right|Illustration of Adie syndrome showing a dilated pupil]] | ||
The primary symptom of Adie syndrome is a tonic pupil, which is a pupil that is abnormally dilated and responds slowly to light. This can lead to difficulties with focusing, especially when transitioning from bright to dim lighting. Patients may also experience blurred vision and sensitivity to light. | |||
In addition to the | In addition to the ocular symptoms, individuals with Adie syndrome often exhibit diminished or absent deep tendon reflexes, particularly in the Achilles tendon. This combination of symptoms is sometimes referred to as Holmes-Adie syndrome. | ||
==Causes== | ==Causes== | ||
| Line 13: | Line 14: | ||
==Diagnosis== | ==Diagnosis== | ||
Diagnosis of Adie syndrome is primarily clinical, based on the characteristic | Diagnosis of Adie syndrome is primarily clinical, based on the characteristic presentation of a tonic pupil and absent reflexes. A thorough eye examination is conducted, and pharmacological testing with dilute pilocarpine may be used to confirm the diagnosis. In Adie syndrome, the affected pupil will constrict more than the normal pupil when exposed to dilute pilocarpine. | ||
==Treatment== | ==Treatment== | ||
There is no cure for Adie syndrome, but treatment focuses on managing symptoms. Reading glasses | There is no cure for Adie syndrome, but treatment focuses on managing symptoms. Reading glasses may be prescribed to help with focusing difficulties. In some cases, pilocarpine eye drops are used to constrict the pupil and improve vision. Patients are also advised to protect their eyes from bright light. | ||
==Prognosis== | ==Prognosis== | ||
Adie syndrome is a benign condition, and while symptoms | Adie syndrome is a benign condition, and while the symptoms can be bothersome, they do not typically lead to serious complications. Over time, the affected pupil may become smaller and less reactive, and reflexes may partially return. | ||
==Related pages== | ==Related pages== | ||
* [[Pupil]] | * [[Pupil]] | ||
* [[ | * [[Parasympathetic nervous system]] | ||
* [[Neurology]] | * [[Neurology]] | ||
* [[ | * [[Reflex]] | ||
[[Category:Neurological disorders]] | [[Category:Neurological disorders]] | ||
[[Category:Eye diseases]] | [[Category:Eye diseases]] | ||
Revision as of 03:58, 13 February 2025
A neurological disorder affecting the pupil of the eye
Adie syndrome, also known as Adie's tonic pupil, is a neurological disorder characterized by a pupil that is larger than normal and reacts slowly to light. It is often associated with absent or diminished deep tendon reflexes. The condition is named after the British neurologist William John Adie.
Signs and symptoms
The primary symptom of Adie syndrome is a tonic pupil, which is a pupil that is abnormally dilated and responds slowly to light. This can lead to difficulties with focusing, especially when transitioning from bright to dim lighting. Patients may also experience blurred vision and sensitivity to light.
In addition to the ocular symptoms, individuals with Adie syndrome often exhibit diminished or absent deep tendon reflexes, particularly in the Achilles tendon. This combination of symptoms is sometimes referred to as Holmes-Adie syndrome.
Causes
The exact cause of Adie syndrome is not well understood, but it is believed to result from damage to the postganglionic fibers of the parasympathetic nervous system that innervate the eye. This damage may be due to a viral or bacterial infection, trauma, or other unknown factors.
Diagnosis
Diagnosis of Adie syndrome is primarily clinical, based on the characteristic presentation of a tonic pupil and absent reflexes. A thorough eye examination is conducted, and pharmacological testing with dilute pilocarpine may be used to confirm the diagnosis. In Adie syndrome, the affected pupil will constrict more than the normal pupil when exposed to dilute pilocarpine.
Treatment
There is no cure for Adie syndrome, but treatment focuses on managing symptoms. Reading glasses may be prescribed to help with focusing difficulties. In some cases, pilocarpine eye drops are used to constrict the pupil and improve vision. Patients are also advised to protect their eyes from bright light.
Prognosis
Adie syndrome is a benign condition, and while the symptoms can be bothersome, they do not typically lead to serious complications. Over time, the affected pupil may become smaller and less reactive, and reflexes may partially return.
