25H-NBOMe: Difference between revisions

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{{Short description|A synthetic psychedelic compound}}
{{DISPLAYTITLE:25H-NBOMe}}
{{Drugbox
| verifiedfields = changed
| verifiedrevid = 477318123
| IUPAC_name = 2-(4-bromo-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamine
| image = 25H-NBOMe.svg
| image_size = 200px
| legal_status = Uncontrolled
| routes_of_administration = [[Intranasal]], [[sublingual]], [[buccal]]
| CAS_number = 1043868-97-8
| ChemSpiderID = 21106326
| PubChem = 44719680
| C=18
| H=22
| Br=1
| N=1
| O=3
| smiles = COc1ccccc1CNCCc2cc(Br)c(OC)c(OC)c2
}}


'''25H-NBOMe''' is a synthetic psychedelic compound that belongs to the [[NBOMe series]]. It is a derivative of the phenethylamine [[2C-H]] and is known for its potent [[hallucinogenic]] effects.  
== 25H-NBOMe ==
[[File:25H-NBOMe.svg|thumb|right|Chemical structure of 25H-NBOMe]]
25H-NBOMe, also known as 2C-H-NBOMe, is a synthetic psychedelic compound belonging to the [[NBOMe series]]. It is a derivative of the phenethylamine 2C-H, modified with a 2-methoxybenzyl (NBOMe) group. This compound is primarily of interest in research settings and is not commonly encountered in recreational use.


==Chemical structure and properties==
=== Chemical Properties ===
25H-NBOMe is chemically classified as a [[phenethylamine]] and a [[substituted amphetamine]]. Its structure consists of a phenethylamine core with a methoxybenzyl group attached to the nitrogen atom. The presence of the 4-bromo-2,5-dimethoxyphenyl group is characteristic of the NBOMe series, contributing to its high affinity for the [[serotonin receptor]]s.
25H-NBOMe is a member of the [[phenethylamine]] class of compounds, which are known for their psychoactive properties. The addition of the NBOMe group to the 2C-H structure significantly alters its pharmacological profile, potentially increasing its affinity for certain [[serotonin receptors]].


==Pharmacology==
=== Pharmacology ===
25H-NBOMe acts primarily as a potent agonist of the [[5-HT2A receptor]], which is responsible for its psychedelic effects. The compound's interaction with this receptor is similar to that of other hallucinogens such as [[LSD]] and [[psilocybin]]. The binding affinity of 25H-NBOMe to the 5-HT2A receptor is significantly higher than that of its parent compound, 2C-H, due to the presence of the N-benzyl substitution.
The pharmacological effects of 25H-NBOMe are not well-documented, but it is believed to act as a partial agonist at the [[5-HT2A receptor]], similar to other compounds in the NBOMe series. This receptor is associated with the psychedelic effects of many hallucinogenic substances.


==Effects==
=== Effects ===
The effects of 25H-NBOMe are similar to those of other psychedelics, including altered perception of time and space, visual hallucinations, and changes in thought processes. The onset of effects typically occurs within 30 to 90 minutes after administration, with the duration lasting up to 12 hours. Due to its potency, 25H-NBOMe is often active at microgram doses.
Due to limited research, the effects of 25H-NBOMe are not fully understood. However, it is likely to produce effects similar to other NBOMe compounds, which can include altered sensory perception, changes in mood, and visual hallucinations. The potency and duration of these effects can vary significantly between individuals.


==Safety and toxicity==
=== Safety and Toxicity ===
The safety profile of 25H-NBOMe is not well-established, and its use has been associated with several adverse effects, including [[vasoconstriction]], [[tachycardia]], and [[hypertension]]. There have been reports of severe toxicity and fatalities associated with its use, often due to overdose or misidentification as other substances.
The safety profile of 25H-NBOMe is not well-established. Compounds in the NBOMe series have been associated with severe adverse effects, including [[vasoconstriction]], [[seizures]], and [[cardiotoxicity]]. As such, caution is advised when handling or studying this compound.


==Legal status==
== Related pages ==
The legal status of 25H-NBOMe varies by country. In some jurisdictions, it is classified as a controlled substance, while in others, it remains unregulated. The compound is often sold online as a "research chemical," which can complicate legal enforcement.
 
==Related pages==
* [[NBOMe series]]
* [[NBOMe series]]
* [[2C-H]]
* [[Phenethylamine]]
* [[5-HT2A receptor]]
* [[5-HT2A receptor]]
* [[Psychedelic drug]]


[[Category:Psychedelic phenethylamines]]
[[Category:Psychedelic phenethylamines]]
[[Category:Serotonin receptor agonists]]
[[Category:NBOMe series]]
[[Category:Designer drugs]]

Latest revision as of 03:58, 13 February 2025


25H-NBOMe[edit]

Chemical structure of 25H-NBOMe

25H-NBOMe, also known as 2C-H-NBOMe, is a synthetic psychedelic compound belonging to the NBOMe series. It is a derivative of the phenethylamine 2C-H, modified with a 2-methoxybenzyl (NBOMe) group. This compound is primarily of interest in research settings and is not commonly encountered in recreational use.

Chemical Properties[edit]

25H-NBOMe is a member of the phenethylamine class of compounds, which are known for their psychoactive properties. The addition of the NBOMe group to the 2C-H structure significantly alters its pharmacological profile, potentially increasing its affinity for certain serotonin receptors.

Pharmacology[edit]

The pharmacological effects of 25H-NBOMe are not well-documented, but it is believed to act as a partial agonist at the 5-HT2A receptor, similar to other compounds in the NBOMe series. This receptor is associated with the psychedelic effects of many hallucinogenic substances.

Effects[edit]

Due to limited research, the effects of 25H-NBOMe are not fully understood. However, it is likely to produce effects similar to other NBOMe compounds, which can include altered sensory perception, changes in mood, and visual hallucinations. The potency and duration of these effects can vary significantly between individuals.

Safety and Toxicity[edit]

The safety profile of 25H-NBOMe is not well-established. Compounds in the NBOMe series have been associated with severe adverse effects, including vasoconstriction, seizures, and cardiotoxicity. As such, caution is advised when handling or studying this compound.

Related pages[edit]