Dogiel cells: Difference between revisions

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'''Dogiel cells''' are a type of [[neuron]] found in the [[autonomic nervous system]]. They were first described by the Russian histologist, [[Alexei Ivanovich Dogiel]], after whom they are named.
{{Short description|A detailed overview of Dogiel cells in the human nervous system}}


==Etymology==
==Overview==
The term "Dogiel cells" is derived from the name of the Russian histologist, [[Alexei Ivanovich Dogiel]], who first described these cells.  
[[Dogiel cells]] are a type of [[neuron]] found in the [[autonomic nervous system]]. They are named after the Russian histologist [[Alexander Dogiel]], who first described them in the late 19th century. These cells are characterized by their unique morphology and are primarily located in the [[sympathetic ganglia]].


==Description==
==Morphology==
Dogiel cells are characterized by their distinct morphology and are classified into two types: Type I and Type II.  
Dogiel cells are known for their distinct shape and structure. They typically have a large, round cell body with multiple dendritic processes extending from it. These dendrites are often highly branched, allowing for extensive synaptic connections with other neurons. The axon of a Dogiel cell is usually long and projects to various target tissues, including [[smooth muscle]], [[glands]], and [[blood vessels]].


'''Type I Dogiel cells''' are found in the [[myenteric plexus]] and have a single axon that branches out into the muscle layers of the gut. These cells are involved in the regulation of [[gastrointestinal motility]].
[[File:Gray799.svg|thumb|right|Diagram of a Dogiel cell in the sympathetic ganglion]]
 
'''Type II Dogiel cells''' are located in the [[submucosal plexus]] and have multiple short dendrites. These cells are involved in the regulation of [[secretion]] and [[blood flow]] in the gut.


==Function==
==Function==
Dogiel cells play a crucial role in the functioning of the [[autonomic nervous system]]. They are involved in the regulation of various physiological processes such as [[gastrointestinal motility]], secretion, and blood flow in the gut.  
The primary function of Dogiel cells is to transmit signals within the autonomic nervous system. They play a crucial role in the regulation of involuntary bodily functions, such as heart rate, digestion, and respiratory rate. By relaying signals from the central nervous system to peripheral organs, Dogiel cells help maintain homeostasis in the body.


==Clinical significance==
==Types of Dogiel Cells==
Abnormalities in Dogiel cells have been associated with various gastrointestinal disorders such as [[Irritable Bowel Syndrome]] (IBS) and [[Inflammatory Bowel Disease]] (IBD).
There are several types of Dogiel cells, each with specific characteristics and functions:


==See also==
* '''Dogiel Type I''': These cells have a multipolar shape with numerous dendrites and are primarily involved in the transmission of excitatory signals.
* [[Neuron]]
* '''Dogiel Type II''': These cells are often bipolar or unipolar and are associated with inhibitory functions.
* [[Autonomic nervous system]]
* '''Dogiel Type III''': Characterized by their large size and extensive dendritic arborization, these cells are involved in complex integrative functions within the ganglia.
* [[Myenteric plexus]]
* [[Submucosal plexus]]


==References==
==Clinical Significance==
<references />
Dogiel cells are important in understanding various autonomic disorders. Dysfunction in these cells can lead to conditions such as [[autonomic neuropathy]], which affects the normal functioning of the autonomic nervous system. Research into Dogiel cells continues to provide insights into the treatment of such disorders.


{{stub}}
==Related pages==
* [[Autonomic nervous system]]
* [[Sympathetic nervous system]]
* [[Neuron]]
* [[Alexander Dogiel]]


[[Category:Neuroscience]]
[[Category:Neuroanatomy]]
[[Category:Histology]]
[[Category:Histology]]
[[Category:Gastroenterology]]

Latest revision as of 03:57, 13 February 2025

A detailed overview of Dogiel cells in the human nervous system


Overview[edit]

Dogiel cells are a type of neuron found in the autonomic nervous system. They are named after the Russian histologist Alexander Dogiel, who first described them in the late 19th century. These cells are characterized by their unique morphology and are primarily located in the sympathetic ganglia.

Morphology[edit]

Dogiel cells are known for their distinct shape and structure. They typically have a large, round cell body with multiple dendritic processes extending from it. These dendrites are often highly branched, allowing for extensive synaptic connections with other neurons. The axon of a Dogiel cell is usually long and projects to various target tissues, including smooth muscle, glands, and blood vessels.

Diagram of a Dogiel cell in the sympathetic ganglion

Function[edit]

The primary function of Dogiel cells is to transmit signals within the autonomic nervous system. They play a crucial role in the regulation of involuntary bodily functions, such as heart rate, digestion, and respiratory rate. By relaying signals from the central nervous system to peripheral organs, Dogiel cells help maintain homeostasis in the body.

Types of Dogiel Cells[edit]

There are several types of Dogiel cells, each with specific characteristics and functions:

  • Dogiel Type I: These cells have a multipolar shape with numerous dendrites and are primarily involved in the transmission of excitatory signals.
  • Dogiel Type II: These cells are often bipolar or unipolar and are associated with inhibitory functions.
  • Dogiel Type III: Characterized by their large size and extensive dendritic arborization, these cells are involved in complex integrative functions within the ganglia.

Clinical Significance[edit]

Dogiel cells are important in understanding various autonomic disorders. Dysfunction in these cells can lead to conditions such as autonomic neuropathy, which affects the normal functioning of the autonomic nervous system. Research into Dogiel cells continues to provide insights into the treatment of such disorders.

Related pages[edit]