Tipepidine: Difference between revisions
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'''Tipepidine''' | {{DISPLAYTITLE:Tipepidine}} | ||
== Tipepidine == | |||
[[File:Tipepidine.svg|thumb|right|Chemical structure of Tipepidine]] | |||
'''Tipepidine''' is a [[cough suppressant]] medication that is used primarily in [[Japan]]. It is known for its antitussive properties and is often prescribed for the treatment of [[cough]] associated with [[respiratory tract infections]]. | |||
== Pharmacology == | == Pharmacology == | ||
Tipepidine acts as a [[sigma receptor]] agonist, which is believed to contribute to its cough suppressant effects. Unlike many other cough suppressants, it does not act on the [[opioid receptor]]s, which reduces the risk of [[addiction]] and [[respiratory depression]]. | |||
=== Mechanism of Action === | |||
The exact mechanism by which tipepidine suppresses cough is not fully understood. However, it is thought to modulate the [[central nervous system]] by interacting with sigma receptors, which are involved in the regulation of [[neurotransmitter]] release and [[neuroplasticity]]. | |||
Tipepidine | == Clinical Use == | ||
Tipepidine is primarily used in the treatment of coughs associated with [[upper respiratory tract infections]]. It is available in various formulations, including [[syrup]]s and [[tablet]]s. The medication is generally well-tolerated, with a low incidence of side effects. | |||
== Side Effects == | == Side Effects == | ||
Common side effects of tipepidine may include mild [[drowsiness]], [[nausea]], and [[dizziness]]. Serious side effects are rare, making it a preferred choice for patients who require long-term cough management. | |||
== History == | |||
Tipepidine was first developed in the 1950s and has been used in clinical practice in Japan for several decades. It has not been widely adopted outside of Japan, but it remains a popular choice for cough suppression in the region. | |||
== | |||
Tipepidine | |||
== Related pages == | |||
* [[Cough suppressant]] | |||
* [[Sigma receptor]] | |||
* [[Respiratory tract infection]] | |||
[[Category:Antitussives]] | [[Category:Antitussives]] | ||
[[Category: | [[Category:Sigma receptor agonists]] | ||
Latest revision as of 03:55, 13 February 2025
Tipepidine[edit]
Tipepidine is a cough suppressant medication that is used primarily in Japan. It is known for its antitussive properties and is often prescribed for the treatment of cough associated with respiratory tract infections.
Pharmacology[edit]
Tipepidine acts as a sigma receptor agonist, which is believed to contribute to its cough suppressant effects. Unlike many other cough suppressants, it does not act on the opioid receptors, which reduces the risk of addiction and respiratory depression.
Mechanism of Action[edit]
The exact mechanism by which tipepidine suppresses cough is not fully understood. However, it is thought to modulate the central nervous system by interacting with sigma receptors, which are involved in the regulation of neurotransmitter release and neuroplasticity.
Clinical Use[edit]
Tipepidine is primarily used in the treatment of coughs associated with upper respiratory tract infections. It is available in various formulations, including syrups and tablets. The medication is generally well-tolerated, with a low incidence of side effects.
Side Effects[edit]
Common side effects of tipepidine may include mild drowsiness, nausea, and dizziness. Serious side effects are rare, making it a preferred choice for patients who require long-term cough management.
History[edit]
Tipepidine was first developed in the 1950s and has been used in clinical practice in Japan for several decades. It has not been widely adopted outside of Japan, but it remains a popular choice for cough suppression in the region.