Lotilaner: Difference between revisions
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{{DISPLAYTITLE:Lotilaner}} | |||
== | == Overview == | ||
[[File:Lotilaner.svg|thumb|right|Chemical structure of Lotilaner]] | |||
'''Lotilaner''' is a chemical compound used as an [[ectoparasiticide]] in veterinary medicine. It belongs to the class of [[isoxazoline]]s, which are known for their efficacy in controlling [[ectoparasites]] such as [[fleas]] and [[ticks]] on animals. Lotilaner is commonly used in products designed for the treatment and prevention of infestations in [[dogs]] and [[cats]]. | |||
Lotilaner | == Mechanism of Action == | ||
Lotilaner works by inhibiting the [[gamma-aminobutyric acid]] (GABA)-gated chloride channels in the nervous system of parasites. This inhibition leads to uncontrolled neuromuscular activity, resulting in the death of the parasite. The selectivity of lotilaner for parasite GABA receptors over those of mammals makes it a safe and effective treatment option for pets. | |||
== | == Pharmacokinetics == | ||
After administration, lotilaner is rapidly absorbed into the bloodstream of the host animal. It has a long half-life, which allows for sustained activity against parasites over a period of time. This pharmacokinetic profile supports its use in monthly dosing regimens for the control of flea and tick infestations. | |||
Lotilaner is | == Uses in Veterinary Medicine == | ||
Lotilaner is primarily used in veterinary medicine for the treatment and prevention of flea and tick infestations in dogs and cats. It is available in various formulations, including oral tablets and topical solutions. The compound is effective against a wide range of ectoparasites, providing comprehensive protection for pets. | |||
== | == Safety and Efficacy == | ||
Clinical studies have demonstrated the safety and efficacy of lotilaner in controlling flea and tick infestations. It is generally well-tolerated by animals, with a low incidence of adverse effects. The compound's efficacy in killing parasites quickly and preventing re-infestation makes it a valuable tool in veterinary parasite control. | |||
== Related Pages == | |||
* [[Isoxazoline]] | |||
* [[Ectoparasiticide]] | |||
* [[Flea]] | |||
* [[Tick]] | |||
* [[Veterinary medicine]] | |||
[[Category:Veterinary drugs]] | |||
[[Category:Ectoparasiticides]] | |||
[[Category:Veterinary | |||
[[Category: | |||
[[Category:Isoxazolines]] | [[Category:Isoxazolines]] | ||
Latest revision as of 03:50, 13 February 2025
Overview[edit]
Lotilaner is a chemical compound used as an ectoparasiticide in veterinary medicine. It belongs to the class of isoxazolines, which are known for their efficacy in controlling ectoparasites such as fleas and ticks on animals. Lotilaner is commonly used in products designed for the treatment and prevention of infestations in dogs and cats.
Mechanism of Action[edit]
Lotilaner works by inhibiting the gamma-aminobutyric acid (GABA)-gated chloride channels in the nervous system of parasites. This inhibition leads to uncontrolled neuromuscular activity, resulting in the death of the parasite. The selectivity of lotilaner for parasite GABA receptors over those of mammals makes it a safe and effective treatment option for pets.
Pharmacokinetics[edit]
After administration, lotilaner is rapidly absorbed into the bloodstream of the host animal. It has a long half-life, which allows for sustained activity against parasites over a period of time. This pharmacokinetic profile supports its use in monthly dosing regimens for the control of flea and tick infestations.
Uses in Veterinary Medicine[edit]
Lotilaner is primarily used in veterinary medicine for the treatment and prevention of flea and tick infestations in dogs and cats. It is available in various formulations, including oral tablets and topical solutions. The compound is effective against a wide range of ectoparasites, providing comprehensive protection for pets.
Safety and Efficacy[edit]
Clinical studies have demonstrated the safety and efficacy of lotilaner in controlling flea and tick infestations. It is generally well-tolerated by animals, with a low incidence of adverse effects. The compound's efficacy in killing parasites quickly and preventing re-infestation makes it a valuable tool in veterinary parasite control.
