ZNF471

ZNF471 is a human gene that encodes a protein known as Zinc Finger Protein 471. This protein is a member of the zinc finger protein family, which is characterized by the presence of zinc finger domains. These domains are protein structures that can bind to DNA, RNA, proteins, and other small molecules.

Function

The exact function of ZNF471 is not fully understood. However, like other zinc finger proteins, it is believed to play a role in gene regulation. Zinc finger proteins can act as transcription factors, binding to specific sequences of DNA and influencing the activity of certain genes.

Clinical Significance

Mutations in ZNF471 have been associated with various diseases. For example, a study published in 2016 found that ZNF471 is frequently methylated and silenced in endometrial cancer, suggesting that it may act as a tumor suppressor gene in this type of cancer.

See Also

• Zinc finger
• Gene regulation
• Endometrial cancer

References

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