OR52N1

OR52N1 is a gene that encodes a protein in humans and is part of the olfactory receptor family. The olfactory receptor family is the largest in the genome. The family members are G-protein coupled receptors that respond to odor molecules and are responsible for our sense of smell.

Function

The OR52N1 gene is thought to have a role in olfaction, the sense of smell. It is one of approximately 400 functional olfactory receptor genes in the human genome. These genes are located in clusters on various chromosomes and are activated by a wide range of odor molecules.

Structure

The OR52N1 gene is located on chromosome 11 in humans. The protein it encodes is a member of the olfactory receptor family, which are seven-transmembrane-domain proteins. These proteins are located in the cell membrane of olfactory receptor neurons in the nose and are responsible for detecting odor molecules in the air.

Clinical significance

While the exact role of OR52N1 in disease is not fully understood, it is thought that variations in this gene may be associated with differences in individuals' sense of smell. Some studies have suggested a link between olfactory receptor genes and conditions such as Parkinson's disease and Alzheimer's disease, although more research is needed in this area.

See also

• Olfactory receptor
• Olfaction
• G protein-coupled receptor
• Parkinson's disease
• Alzheimer's disease

References

<references />

   This article is a medical stub. You can help WikiMD by expanding it!