MPPF

MPPF (4,4'-Methylenediphenyl diisocyanate) is a potent and selective antagonist of the serotonin 5-HT1A receptor. It is used in scientific research to study the role of the 5-HT1A receptor in the action of drugs and in various biological processes.

Chemistry

MPPF is a chemical compound with the molecular formula C17H15NO2. It is a derivative of phenylisocyanate, with two phenyl groups attached to a central carbon atom. The compound is a solid at room temperature and is soluble in organic solvents.

Pharmacology

MPPF acts as an antagonist at the 5-HT1A receptor, meaning it blocks the action of serotonin at this receptor. This makes it a useful tool in research to study the role of the 5-HT1A receptor in various biological processes, including mood regulation, anxiety, and the action of certain drugs.

Uses in Research

MPPF has been used in a variety of research studies to investigate the role of the 5-HT1A receptor. For example, it has been used to study the effects of drugs that act on the 5-HT1A receptor, such as antidepressants and anxiolytics. It has also been used to investigate the role of the 5-HT1A receptor in mood regulation and anxiety.

Safety

As with all chemicals, MPPF should be handled with care. It is not intended for human consumption and should be used only in a laboratory setting by trained professionals.

See Also

• 5-HT1A receptor
• Serotonin
• Antagonist (pharmacology)
• Phenylisocyanate

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