OR2G2

OR2G2 is a gene that encodes a protein in humans. It is also known as olfactory receptor, family 2, subfamily G, member 2. This gene is part of the olfactory receptor gene family, which is the largest gene family in the genome. The olfactory receptors are G protein-coupled receptors that are involved in the detection of odor molecules.

Function

The OR2G2 gene is a member of the olfactory receptor family of genes. Olfactory receptors interact with odorant molecules in the nose to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein coupled receptors (GPCR) arising from single coding-exon genes.

Structure

The OR2G2 gene is located on chromosome 1, specifically at 1q44. It spans a length of approximately 1.1 kb and consists of a single coding exon. The encoded protein has 7 transmembrane domains, which is characteristic of G protein-coupled receptors.

Clinical Significance

While the specific role of OR2G2 in human health and disease is not fully understood, olfactory receptors in general are known to play a role in a variety of physiological processes. For example, they are involved in the detection of environmental chemicals, including toxins and pollutants. They also play a role in the perception of taste and the regulation of appetite and satiety.

Research

Research into the OR2G2 gene and its associated protein is ongoing. Understanding the function and regulation of this gene could provide insights into the complex process of olfaction and potentially lead to the development of new treatments for disorders related to smell and taste.

See Also

• Olfactory receptor
• G protein-coupled receptor
• Gene
• Protein

References

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